Orthologous receptor kinases quantitatively affect the host status of barley to leaf rust fungi

doi:10.1038/s41477-019-0545-2

	Orthologous receptor kinases quantitatively affect the host status of barley to leaf rust fungi
	Wang, Yajun ; Subedi, Sudeep 5; de Vries, Harmen ; Doornenbal, Pieter ; Vels, Anton ; Hensel, Goetz 2; Kumlehn, Jochen 2; Johnston, Paul A.; Qi, Xiaoquan4 ; Blilou, Ikram ; Niks, Rients E.; Krattinger, Simon G.
	2019
发表期刊	NATURE PLANTS
ISSN	2055-026X
卷号	5 期号:11 页码:1129-1135
摘要	Global food security depends on cereal crops with durable disease resistance. Most cereals are colonized by rust fungi, which are pathogens of major significance for global agriculture(1). Cereal rusts display a high degree of host specificity and one rust species or forma specialis generally colonizes only one cereal host(2). Exploiting the non-host status and transferring non-host resistance genes between cereal crop species has been proposed as a strategy for durable rust resistance breeding. The molecular determinants that define the host status to rusts, however, are largely unknown. Here, we show that orthologous genes at the Rphq2 locus for quantitative leaf rust resistance from cultivated barley(3) and Rph22 from wild bulbous barley(4) affect the host status to leaf rusts. Both genes encode lectin receptor-like kinases. We transformed Rphq2 and Rph22 into an experimental barley line that has been bred for susceptibility to non-adapted leaf rusts, which allowed us to quantify resistance responses against various leaf rust species. Rphq2 conferred a much stronger resistance to the leaf rust of wild bulbous barley than to the leaf rust adapted to cultivated barley, while for Rph22 the reverse was observed. We hypothesize that adapted leaf rust species mitigate perception by cognate host receptors by lowering ligand recognition. Our results provide an example of orthologous genes that connect the quantitative host with non-host resistance to cereal rusts. Such genes provide a basis to exploit non-host resistance in molecular breeding.
学科领域	Plant Sciences
DOI	10.1038/s41477-019-0545-2
收录类别	SCI
语种	英语
WOS关键词	PARTIAL RESISTANCE ; PUCCINIA-HORDEI ; DISEASE RESISTANCE ; NONHOST ; GENES ; IDENTIFICATION ; SPECIFICITY ; LINES
WOS研究方向	Plant Sciences
WOS记录号	WOS:000496526100012
出版者	NATURE PUBLISHING GROUP
文献子类	Article
出版地	LONDON
EISSN	2055-0278
资助机构	King Abdullah University of Science and Technology Office of Sponsored ResearchKing Abdullah University of Science & Technology [OSR-CRG2018-3768] ; New Zealand Institute for Plant & Food Research Limited Strategic Science Investment Fund ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31471756] ; NWO-ALW as part of the ERA-CAPS project [849.13.002, DURESTrit 13.006]
作者邮箱	rients.niks@wur.nl ; simon.krattinger@kaust.edu.sa
作品OA属性	Green Submitted
引用统计	被引频次：41[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/19814
专题	中科院植物分子生理学重点实验室
作者单位	1.[Wang, Yajun; Subedi, Sudeep; de Vries, Harmen; Doornenbal, Pieter; Vels, Anton; Niks, Rients E.] Wageningen Univ & Res, Plant Breeding, Wageningen, Netherlands 2.Wang, Yajun; Blilou, Ikram; Krattinger, Simon G.] King Abdullah Univ Sci & Technol, Biol & Environm Sci & Engn Div, Ctr Desert Agr, Thuwal, Saudi Arabia 3.Leibniz Inst Plant Genet & Crop Plant Res IPK Gat, Plant Reprod Biol, Gatersleben, Germany 4.Johnston, Paul A.] New Zealand Inst Plant & Food Res Ltd, Lincoln, New Zealand 5.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing, Peoples R China 6.Nepal Agr Res Council, Kathmandu, Nepal
推荐引用方式 GB/T 7714	Wang, Yajun,Subedi, Sudeep,de Vries, Harmen,et al. Orthologous receptor kinases quantitatively affect the host status of barley to leaf rust fungi[J]. NATURE PLANTS,2019,5(11):1129-1135.
APA	Wang, Yajun.,Subedi, Sudeep.,de Vries, Harmen.,Doornenbal, Pieter.,Vels, Anton.,...&Krattinger, Simon G..(2019).Orthologous receptor kinases quantitatively affect the host status of barley to leaf rust fungi.NATURE PLANTS,5(11),1129-1135.
MLA	Wang, Yajun,et al."Orthologous receptor kinases quantitatively affect the host status of barley to leaf rust fungi".NATURE PLANTS 5.11(2019):1129-1135.

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