Knowledge Management System Of Institute Of Botany,CAS
DNA methylation footprints during soybean domestication and improvement | |
Shen, Yanting; Zhang, Jixiang; Liu, Yucheng; Liu, Shulin; Liu, Zhi; Duan, Zongbiao; Wang, Zheng; Zhu, Baoge; Guo, Ya-Long; Tian, Zhixi2 | |
2018 | |
发表期刊 | GENOME BIOLOGY |
ISSN | 1474-760X |
卷号 | 19 |
摘要 | Background: In addition to genetic variation, epigenetic variation plays an important role in determining various biological processes. The importance of natural genetic variation to crop domestication and improvement has been widely investigated. However, the contribution of epigenetic variation in crop domestication at population level has rarely been explored. Results: To understand the impact of epigenetics on crop domestication, we investigate the variation of DNA methylation during soybean domestication and improvement by whole-genome bisulfite sequencing of 45 soybean accessions, including wild soybeans, landraces, and cultivars. Through methylomic analysis, we identify 5412 differentially methylated regions (DMRs). These DMRs exhibit characters distinct from those of genetically selected regions. In particular, they have significantly higher genetic diversity. Association analyses suggest only 22.54% of DMRs can be explained by local genetic variations. Intriguingly, genes in the DMRs that are not associated with any genetic variation are enriched in carbohydrate metabolism pathways. Conclusions: This study provides a valuable map of DNA methylation across diverse accessions and dissects the relationship between DNA methylation variation and genetic variation during soybean domestication, thus expanding our understanding of soybean domestication and improvement. |
关键词 | DNA methylation Domestication Soybean |
学科领域 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
DOI | 10.1186/s13059-018-1516-z |
收录类别 | SCI |
语种 | 英语 |
WOS关键词 | GENOME-WIDE ASSOCIATION ; NATURAL EPIGENETIC VARIATION ; ARABIDOPSIS-THALIANA ; AGRONOMIC TRAITS ; TRANSPOSABLE ELEMENTS ; EPIGENOMIC DIVERSITY ; ANALYSIS TOOLKIT ; SEQUENCING DATA ; PLANT ; POPULATION |
WOS记录号 | WOS:000444255100001 |
出版者 | BMC |
文献子类 | Article |
出版地 | LONDON |
资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [91531304, 31525018, 31788103] ; Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA08000000] |
作者邮箱 | zxtian@genetics.ac.cn |
作品OA属性 | gold, Green Published |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ibcas.ac.cn/handle/2S10CLM1/20339 |
专题 | 系统与进化植物学国家重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Plant Cell & Chromosome Engn, Beijing 100101, Peoples R China 2.Chinese Acad Sci, State Key Lab Systemat & Evolutionary Bot, Inst Bot, Beijing 100093, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
推荐引用方式 GB/T 7714 | Shen, Yanting,Zhang, Jixiang,Liu, Yucheng,et al. DNA methylation footprints during soybean domestication and improvement[J]. GENOME BIOLOGY,2018,19. |
APA | Shen, Yanting.,Zhang, Jixiang.,Liu, Yucheng.,Liu, Shulin.,Liu, Zhi.,...&Tian, Zhixi.(2018).DNA methylation footprints during soybean domestication and improvement.GENOME BIOLOGY,19. |
MLA | Shen, Yanting,et al."DNA methylation footprints during soybean domestication and improvement".GENOME BIOLOGY 19(2018). |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Shen-2018-DNA methyl(1815KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论