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| Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor | |
| Qiu, Nianwei; Wang, Renjun; Sun, Yuan; Wang, Xiushun1,2; Jiang, Dacheng; Meng, Yuting; Zhou, Feng3 | |
| 2018 | |
| Source Publication | CHEMOSPHERE
 |
| ISSN | 0045-6535 |
| Volume | 193Pages:711-719 |
| Abstract | To investigate the toxic effect and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in aquatic plants, in vivo and in vitro exposure to BDE-47 were conducted. After 14-d exposure to 5-20 mu g/L BDE-47, the growth of Lemna minor plants was significantly suppressed, and the chlorophyll and soluble protein contents in fronds markedly decreased. Accordingly, the photosynthetic efficiency (Fv/Fm, PI) decreased. When the thylakoid membranes isolated from healthy fronds was exposed to 5-20 mg/L BDE-47 directly in vitro for 1 h, the photosynthetic efficiency also decreased significantly. In both the in vitro (5-20 mu g/L) and in vivo (5-20 mg/L) experiments, BDE-47 led to an increased plasma membrane permeability. Hence, we concluded that BDE-47 had a direct toxicity to photosynthetic membranes and plasma membranes. However, direct effects on the activities of peroxidase (POD), malate dehydrogenase (MDH) and nitroreductase (NR) were not observed by adding 5-20 mg/L BDE-47 into crude enzyme extracts. The malondialdehyde (MDA) and superoxide anion radical (O-2(-)) contents in the BDE-47 treated fronds were higher than those in the control fronds, suggesting that L. minor can not effectively relieve reactive oxygen species (ROS). The data above indicates that BDE-47 is toxic to L. minor through acting directly on biomembranes, which induces the production of ROS and thus causes remarkable oxidative damage to cells. (C) 2017 Elsevier Ltd. All rights reserved. |
| Keyword | 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) Lemna minor Toxic effects Toxic mechanism Chronic toxicity Direct toxicity |
| Subject Area | Environmental Sciences |
| DOI | 10.1016/j.chemosphere.2017.10.148 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | POLYBROMINATED DIPHENYL ETHERS ; POLYCHLORINATED-BIPHENYLS PCBS ; MITOCHONDRIAL BIOENERGETICS ; ANTIOXIDATIVE ENZYMES ; SUPEROXIDE-DISMUTASE ; LIPID-PEROXIDATION ; NITRATE REDUCTASE ; OXIDATIVE STRESS ; POTENTIAL ROLE ; CHLOROPHYLL-A |
| WOS ID | WOS:000423890500084 |
| Publisher | PERGAMON-ELSEVIER SCIENCE LTD |
| Subtype | Article |
| Publication Place | OXFORD |
| EISSN | 1879-1298 |
| Funding Organization | Natural Science Foundation of Shandong ProvinceNatural Science Foundation of Shandong Province [ZR2015JL012, ZR2015DL009] ; Postgraduate Education Innovation Project of Shandong Province [SDYY16087] ; China's Post-doctoral Science FundChina Postdoctoral Science Foundation [2016M592158] |
| Corresponding Author Email | zhoufeng@njxzc.edu.cn |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ibcas.ac.cn/handle/2S10CLM1/20464 |
| Collection | 中科院光生物学重点实验室 |
| Affiliation | 1.Qufu Normal Univ, Sch Life Sci, Qufu 273165, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Photosynth Res Ctr, Beijing 100093, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Nanjing Xiaozhuang Univ, Sch Food Sci, Nanjing 211171, Jiangsu, Peoples R China |
| Recommended Citation GB/T 7714 | Qiu, Nianwei,Wang, Renjun,Sun, Yuan,et al. Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor[J]. CHEMOSPHERE,2018,193:711-719. |
| APA | Qiu, Nianwei.,Wang, Renjun.,Sun, Yuan.,Wang, Xiushun.,Jiang, Dacheng.,...&Zhou, Feng.(2018).Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor.CHEMOSPHERE,193,711-719. |
| MLA | Qiu, Nianwei,et al."Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor".CHEMOSPHERE 193(2018):711-719. |
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| 1-s2.0-S004565351731（1268KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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