Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor

doi:10.1016/j.chemosphere.2017.10.148

IB-CAS > 中科院光生物学重点实验室

	Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor
	Qiu, Nianwei ; Wang, Renjun ; Sun, Yuan ; Wang, Xiushun 1,2; Jiang, Dacheng ; Meng, Yuting ; Zhou, Feng 3
	2018
发表期刊	CHEMOSPHERE
ISSN	0045-6535
卷号	193 页码:711-719
摘要	To investigate the toxic effect and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in aquatic plants, in vivo and in vitro exposure to BDE-47 were conducted. After 14-d exposure to 5-20 mu g/L BDE-47, the growth of Lemna minor plants was significantly suppressed, and the chlorophyll and soluble protein contents in fronds markedly decreased. Accordingly, the photosynthetic efficiency (Fv/Fm, PI) decreased. When the thylakoid membranes isolated from healthy fronds was exposed to 5-20 mg/L BDE-47 directly in vitro for 1 h, the photosynthetic efficiency also decreased significantly. In both the in vitro (5-20 mu g/L) and in vivo (5-20 mg/L) experiments, BDE-47 led to an increased plasma membrane permeability. Hence, we concluded that BDE-47 had a direct toxicity to photosynthetic membranes and plasma membranes. However, direct effects on the activities of peroxidase (POD), malate dehydrogenase (MDH) and nitroreductase (NR) were not observed by adding 5-20 mg/L BDE-47 into crude enzyme extracts. The malondialdehyde (MDA) and superoxide anion radical (O-2(-)) contents in the BDE-47 treated fronds were higher than those in the control fronds, suggesting that L. minor can not effectively relieve reactive oxygen species (ROS). The data above indicates that BDE-47 is toxic to L. minor through acting directly on biomembranes, which induces the production of ROS and thus causes remarkable oxidative damage to cells. (C) 2017 Elsevier Ltd. All rights reserved.
关键词	2,2',4,4'-tetrabromodiphenyl ether (BDE-47) Lemna minor Toxic effects Toxic mechanism Chronic toxicity Direct toxicity
学科领域	Environmental Sciences
DOI	10.1016/j.chemosphere.2017.10.148
收录类别	SCI
语种	英语
WOS关键词	POLYBROMINATED DIPHENYL ETHERS ; POLYCHLORINATED-BIPHENYLS PCBS ; MITOCHONDRIAL BIOENERGETICS ; ANTIOXIDATIVE ENZYMES ; SUPEROXIDE-DISMUTASE ; LIPID-PEROXIDATION ; NITRATE REDUCTASE ; OXIDATIVE STRESS ; POTENTIAL ROLE ; CHLOROPHYLL-A
WOS记录号	WOS:000423890500084
出版者	PERGAMON-ELSEVIER SCIENCE LTD
文献子类	Article
出版地	OXFORD
EISSN	1879-1298
资助机构	Natural Science Foundation of Shandong ProvinceNatural Science Foundation of Shandong Province [ZR2015JL012, ZR2015DL009] ; Postgraduate Education Innovation Project of Shandong Province [SDYY16087] ; China's Post-doctoral Science FundChina Postdoctoral Science Foundation [2016M592158]
作者邮箱	zhoufeng@njxzc.edu.cn
引用统计	被引频次：18[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/20464
专题	中科院光生物学重点实验室
作者单位	1.Qufu Normal Univ, Sch Life Sci, Qufu 273165, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Photosynth Res Ctr, Beijing 100093, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Nanjing Xiaozhuang Univ, Sch Food Sci, Nanjing 211171, Jiangsu, Peoples R China
推荐引用方式 GB/T 7714	Qiu, Nianwei,Wang, Renjun,Sun, Yuan,et al. Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor[J]. CHEMOSPHERE,2018,193:711-719.
APA	Qiu, Nianwei.,Wang, Renjun.,Sun, Yuan.,Wang, Xiushun.,Jiang, Dacheng.,...&Zhou, Feng.(2018).Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor.CHEMOSPHERE,193,711-719.
MLA	Qiu, Nianwei,et al."Toxic effects and mechanism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on Lemna minor".CHEMOSPHERE 193(2018):711-719.

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