Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony)

doi:10.1016/j.phytochem.2017.11.008

	Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony)
	Li, Shan-Shan ; Wu, Qian ; Yin, Dan-Dan ; Feng, Cheng-Yong ; Liu, Zheng-An; Wang, Liang-Sheng
	2018
发表期刊	PHYTOCHEMISTRY
ISSN	0031-9422
卷号	146 页码:16-24
摘要	Mu Dan Pi is a traditional Chinese medicine used to treat inflammation, cancer, allergies, diabetes, angiocardiopathy, and neurodegenerative diseases. In this study, the metabolome variation within Mu Dan Pi collected from 372 tree peony cultivars was systematically investigated. In total, 42 metabolites were identified, comprising of 14 monoterpene glucosides, 11 tannins, 8 paeonols, 6 flavonoids, and 3 phenols. All cultivars revealed similar metabolite profiles, however, they were further classified into seven groups on the basis of their varying metabolite contents by hierarchical cluster analysis. Traditional cultivars for Mu Dan Pi were found to have very low metabolite contents, falling into clusters I and II. Cultivars with the highest amounts of metabolites were grouped in clusters VI and VII. Five potential cultivars, namely, 'Bai Yuan Qi Guan', 'Cao Zhou Hong', 'Da Zong Zi', 'Sheng Dan Lu', and 'Cheng Xin', with high contents of monoterpene glycosides, tannins, and paeonols, were further screened. Interestingly, the majority of investigated cultivars had relatively higher metabolite contents compared to the traditional medicinal tree peony cultivars. (C) 2017 Elsevier Ltd. All rights reserved.
关键词	Mu Dan Pi Paeonia UPLC Metabolomics Monoterpene glycoside Tannin Paeonol Flavonoid
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
DOI	10.1016/j.phytochem.2017.11.008
收录类别	SCI
语种	英语
WOS关键词	CORTEX MOUTAN ; PC12 CELLS ; MICE ; INHIBITION ; APOPTOSIS ; INFLAMMATION ; ANTITUMOR ; PATHWAY ; ROOTS ; RATS
WOS记录号	WOS:000423895200003
出版者	PERGAMON-ELSEVIER SCIENCE LTD
文献子类	Article
出版地	OXFORD
资助机构	Beijing Municipal Science and Technology Plan Project [Z161100000916015] ; National High Technology Research and Development Program of China (863 Program)National High Technology Research and Development Program of China [2011AA10020702]
作者邮箱	liuzhengan@ibcas.ac.cn ; wanglsh@ibcas.ac.cn
引用统计	被引频次：41[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/20657
专题	中科院北方资源植物重点实验室
作者单位	1.[Li, Shan-Shan 2.Wu, Qian 3.Yin, Dan-Dan 4.Feng, Cheng-Yong 5.Liu, Zheng-An 6.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing Bot Garden, Beijing 100093, Peoples R China 7.[Wu, Qian 8.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Li, Shan-Shan,Wu, Qian,Yin, Dan-Dan,et al. Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony)[J]. PHYTOCHEMISTRY,2018,146:16-24.
APA	Li, Shan-Shan,Wu, Qian,Yin, Dan-Dan,Feng, Cheng-Yong,Liu, Zheng-An,&Wang, Liang-Sheng.(2018).Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony).PHYTOCHEMISTRY,146,16-24.
MLA	Li, Shan-Shan,et al."Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony)".PHYTOCHEMISTRY 146(2018):16-24.

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