A selfish genetic element confers non-Mendelian inheritance in rice

doi:10.1126/science.aar4279

	A selfish genetic element confers non-Mendelian inheritance in rice
	Yu, Xiaowen ; Zhao, Zhigang ; Zheng, Xiaoming 1; Zhou, Jiawu 2; Kong, Weiyi ; Wang, Peiran ; Bai, Wenting ; Zheng, Hai ; Zhang, Huan ; Li, Jing 2; Liu, Jiafan 1; Wang, Qiming ; Zhang, Long ; Liu, Kai ; Yu, Yang ; Guo, Xiuping 1; Wang, Jiulin 1; Lin, Qibing 1; Wu, Fuqing 1; Ren, Yulong 1; Zhu, Shanshan 1; Zhang, Xin 1; Cheng, Zhijun 1; Lei, Cailin 1; Liu, Shijia ; Liu, Xi ; Tian, Yunlu ; Jiang, Ling ; Ge, Song3 ; Wu, Chuanyin 1; Tao, Dayun 2; Wang, Haiyang 1; Wan, Jianmin 1
	2018
Source Publication	SCIENCE
ISSN	0036-8075
Volume	360 Issue:6393 Pages:1130-1132
Abstract	Selfish genetic elements are pervasive in eukaryote genomes, but their role remains controversial. We show that qHMSZ a major quantitative genetic locus for hybrid male sterility between wild rice (Oryza meridionalis) and Asian cultivated rice (O. sativa), contains two tightly linked genes [Open Reading Frame 2 (ORF2) and ORF3]. ORF2 encodes a toxic genetic element that aborts pollen in a sporophytic manner, whereas ORF3 encodes an antidote that protects pollen in a gametophytic manner. Pollens lacking ORF3 are selectively eliminated, leading to segregation distortion in the progeny. Analysis of the genetic sequence suggests that ORF3 arose first, followed by gradual functionalization of ORF2. Furthermore, this toxin-antidote system may have promoted the differentiation and/or maintained the genome stability of wild and cultivated rice.
Subject Area	Multidisciplinary Sciences
DOI	10.1126/science.aar4279
Indexed By	SCI
Language	英语
WOS Keyword	HYBRID MALE-STERILITY
WOS ID	WOS:000434635500049
Publisher	AMER ASSOC ADVANCEMENT SCIENCE
Subtype	Article
Publication Place	WASHINGTON
EISSN	1095-9203
Funding Organization	National Key Research and Development Program of China [2016YFD0100301] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [U1502265] ; Agricultural Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences
Corresponding Author Email	wuchuanyin@caas.cn ; taody12@aliyun.com ; wanghaiyang@caas.cn ; wanjianmin@caas.cn
Citation statistics	Cited Times:58[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.ibcas.ac.cn/handle/2S10CLM1/20716
Collection	系统与进化植物学国家重点实验室
Affiliation	1.Nanjing Agr Univ, Natl Key Lab Crop Genet & Germplasm Enhancement, Jiangsu Plant Gene Engn Res Ctr, Nanjing 210095, Jiangsu, Peoples R China 2.Chinese Acad Agr Sci, Inst Crop Sci, Natl Key Facil Crop Gene Resources & Genet Improv, Beijing 100081, Peoples R China 3.Yunnan Acad Agr Sci, Food Crops Res Inst, Kunming 650200, Yunnan, Peoples R China 4.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China
Recommended Citation GB/T 7714	Yu, Xiaowen,Zhao, Zhigang,Zheng, Xiaoming,et al. A selfish genetic element confers non-Mendelian inheritance in rice[J]. SCIENCE,2018,360(6393):1130-1132.
APA	Yu, Xiaowen.,Zhao, Zhigang.,Zheng, Xiaoming.,Zhou, Jiawu.,Kong, Weiyi.,...&Wan, Jianmin.(2018).A selfish genetic element confers non-Mendelian inheritance in rice.SCIENCE,360(6393),1130-1132.
MLA	Yu, Xiaowen,et al."A selfish genetic element confers non-Mendelian inheritance in rice".SCIENCE 360.6393(2018):1130-1132.

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