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| Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation | |
Zhang, Xuan1; Lin, Kangqi1; Li, Yinxin
| |
| 2020 | |
| Source Publication | PLANT PHYSIOLOGY AND BIOCHEMISTRY
 |
| ISSN | 0981-9428 |
| Volume | 155Pages:637-649 |
| Abstract | Phytosterols are a group of sterols exclusive to plants and fungi, but are indispensable to humans because of their medicinal and nutritional values. However, current raw materials used for phytosterols extraction add to the cost and waste in the process. For higher sterols production, major attention is drawn to plant materials abundant in phytosterols and genetic modification. To provide an insight into phytosterols metabolism, the research progress on key enzymes involved in phytosterols biosynthesis and conversions were summarized. CAS, SSR2, SMT, DWFI and CYP710A, the enzymes participating in the biosynthetic pathway, and PSAT, ASAT and SGT, the enzymes involved in the conversion of free sterols to conjugated ones, were reviewed. Specifically, SMT and CYP710A were emphasized for their function on modulating the percentage composition of different kinds of phytosterols. The thresholds of sterol equilibrium and the resultant phytosterols accumulation, which vary in plant species and contribute to plasma membrane remodeling under stresses, were also discussed. By retrospective analysis of the previous researches, we proposed a feedback mechanism regulating sterol equilibrium underlying sterols metabolism. From a strategic perspective, we regard salt tolerant plant as an alternative to present raw materials, which will attain higher phytosterols production in combination with gene-modification. |
| Keyword | Phytosterols biosynthesis Phytosterols conversion Sterol equilibrium Feedback regulation Plasma membrane remodeling |
| Subject Area | Plant Sciences |
| DOI | 10.1016/j.plaphy.2020.08.021 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | MEMBRANE LIPID-COMPOSITION ; STEROL C-22 DESATURASE ; PLASMA-MEMBRANE ; ARABIDOPSIS-THALIANA ; CYCLOARTENOL SYNTHASE ; FUNCTIONAL-ANALYSIS ; EMBRYO DEVELOPMENT ; MOLECULAR-CLONING ; ESTER SYNTHESIS ; CELL VIABILITY |
| WOS Research Area | Plant Sciences |
| WOS ID | WOS:000581918000062 |
| Publisher | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER |
| Subtype | Review |
| Publication Place | ISSY-LES-MOULINEAUX |
| Funding Organization | Strategic Priority Research Program of Chinese Academy of SciencesChinese Academy of Sciences [XDA24010306] ; Chinese Ministry of AgricultureMinistry of Agriculture, China [2016ZX08009-003-002] ; Major Science and Technology Innovation Project of Shandong Province [2019JZZY010726] |
| Corresponding Author Email | zhangxuan@ibcas.ac.cn ; linkangqi@ibcas.ac.cn ; yxli@ibcas.ac.cn |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ibcas.ac.cn/handle/2S10CLM1/21543 |
| Collection | 中科院植物分子生理学重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Zhang, Xuan,Lin, Kangqi,Li, Yinxin. Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation[J]. PLANT PHYSIOLOGY AND BIOCHEMISTRY,2020,155:637-649. |
| APA | Zhang, Xuan,Lin, Kangqi,&Li, Yinxin.(2020).Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation.PLANT PHYSIOLOGY AND BIOCHEMISTRY,155,637-649. |
| MLA | Zhang, Xuan,et al."Highlights to phytosterols accumulation and equilibrium in plants: Biosynthetic pathway and feedback regulation".PLANT PHYSIOLOGY AND BIOCHEMISTRY 155(2020):637-649. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S098194282030（4062KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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