Knowledge Management System Of Institute Of Botany,CAS
Revealing the effects of multi-scale molecules on alpha-linolenic acid-loaded W-1/O/W-2 microemulsion: A combined study from physical properties, antioxidant capacity and in vitro release kinetics | |
Li, Qing; Liu, Xiaoxue; Byambasuren, Khorolgarav; Wang, Xueping; Qiu, Shuang; Gao, Yujie; Dang, Leping; Liu, Zhengan1; Shu, Qingyan1; Wang, Zhanzhong | |
2020 | |
发表期刊 | JOURNAL OF MOLECULAR LIQUIDS |
ISSN | 0167-7322 |
卷号 | 303 |
摘要 | The effects of multi-scale molecules on physical properties, antioxidant capacity and in vitro release kinetics in the alpha-linolenic acid-loaded water-in-oil-in-water (W-1/O/W-2) microemulsion were revealed in this work. The glucose and carboxymethyl cellulose sodium (CMC) solutions were selected as the internal aqueous phase (W-1) of the microemulsion, respectively, while the multi-scale molecules, such as sodium chloride (NaCl), glycine (Gly), glucose (Glu), CMC, bovine serum albumin (BSA) and sodium caseinate (SC), were added in the external aqueous phase (W-2) to balance the osmotic pressure and meanwhile their effects on the fluorescence property, antioxidant capacity and release kinetics were probed. Among these, the CMCw1-NaClw2 and Glu(w1)-CMCw2 microemulsion within the appropriate concentration range could dramatically increase the storage stability and antioxidant capacity by inhibiting the aggregation of droplets or Ostwald ripening, while the addition of Gly and SC had the negative effect on the stability of microemulsion. Finally, the release kinetic dates were fitted and the Koismeyer-Peppas equation was considered as the most suitable to explain the ALA release kinetics that were controlled by diffusion and erosion in the simulated gastric fluid (SGF, pH = 2.0) and simulated intestinal fluid (SIF, pH = 6.8). The application of release kinetic models in nutrient nano-delivery systems could facilitate the investigation on the release mechanism of nutritional components. (C) 2020 Published by Elsevier B.V. |
关键词 | W1/O/W-2 microemulsion Multi-scale molecules Properties Antioxidant capacity Release kinetics |
学科领域 | Chemistry, Physical ; Physics, Atomic, Molecular & Chemical |
DOI | 10.1016/j.molliq.2020.112675 |
收录类别 | SCI |
语种 | 英语 |
WOS关键词 | MULTIPLE W/O/W EMULSIONS ; STABILITY ; DELIVERY ; EMULSIFICATION ; ADDITIVES ; PROFILES ; BEHAVIOR ; SYSTEMS |
WOS研究方向 | Chemistry ; Physics |
WOS记录号 | WOS:000533612700078 |
出版者 | ELSEVIER |
文献子类 | Article |
出版地 | AMSTERDAM |
EISSN | 1873-3166 |
资助机构 | Strategic Priority Research Program of the Chinese Academy of SciencesChinese Academy of Sciences [XDA23080601] ; Tianjin Municipal Natural Science FoundationNatural Science Foundation of Tianjin [17JCYBJC20400] |
作者邮箱 | shuqy@ibcas.ac.cn ; wzz7698@tju.edu.cn |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ibcas.ac.cn/handle/2S10CLM1/21760 |
专题 | 中科院北方资源植物重点实验室 |
作者单位 | 1.Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China 2.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing Bot Garden, Beijing 100093, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Qing,Liu, Xiaoxue,Byambasuren, Khorolgarav,et al. Revealing the effects of multi-scale molecules on alpha-linolenic acid-loaded W-1/O/W-2 microemulsion: A combined study from physical properties, antioxidant capacity and in vitro release kinetics[J]. JOURNAL OF MOLECULAR LIQUIDS,2020,303. |
APA | Li, Qing.,Liu, Xiaoxue.,Byambasuren, Khorolgarav.,Wang, Xueping.,Qiu, Shuang.,...&Wang, Zhanzhong.(2020).Revealing the effects of multi-scale molecules on alpha-linolenic acid-loaded W-1/O/W-2 microemulsion: A combined study from physical properties, antioxidant capacity and in vitro release kinetics.JOURNAL OF MOLECULAR LIQUIDS,303. |
MLA | Li, Qing,et al."Revealing the effects of multi-scale molecules on alpha-linolenic acid-loaded W-1/O/W-2 microemulsion: A combined study from physical properties, antioxidant capacity and in vitro release kinetics".JOURNAL OF MOLECULAR LIQUIDS 303(2020). |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
165558.pdf(2444KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论