OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature

doi:10.1016/j.devcel.2020.03.009

	OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature
	Tang, Yongyan ; Gao, Chun-Chun ; Gao, Ying ; Yang, Ying ; Shi, Boyang ; Yu, Jia-Li ; Lyu, Cong ; Sun, Bao-Fa ; Wang, Hai-Lin ; Xu, Yunyuan 6; Yang, Yun-Gui ; Chong, Kang 2,6
	2020
发表期刊	DEVELOPMENTAL CELL
ISSN	1534-5807
卷号	53 期号:3 页码:272-296
摘要	Extreme weather events can cause heat stress that decreases crop production. Recent studies have demonstrated that protein degradation and rRNA homeostasis as well as transcription factors are involved in the thermoresponse in plants. However, how RNA modifications contribute to temperature stress response in plant remains largely unknown. Herein, we identified OsNSUN2 as an RNA 5-methylcytosine (m(5)C) methyltransferase in rice. osnsun2 mutant displayed severe temperature- and light-dependent lesion-mimic phenotypes and heat-stress hypersensitivity. Heat stress enhanced the OsNSUN2-dependent m(5)C modification of mRNAs involved in photosynthesis and detoxification systems, such as beta-OsLCY, OsHO2, OsPAL1, and OsGLYI4, which increased protein synthesis. Furthermore, the photosystem of osnsun2 mutant was vulnerable to high ambient temperature and failed to undergo repair under tolerable heat stress. Thus, OsNSUN2 mutation reduced photosynthesis efficiency and accumulated excessive reactive oxygen species upon heat treatment, Our findings demonstrate an important mechanism of mRNA m(5)C-dependent heat acclimation in rice.
学科领域	Cell Biology ; Developmental Biology
DOI	10.1016/j.devcel.2020.03.009
收录类别	SCI
语种	英语
WOS关键词	CHLOROPHYLL SYNTHESIS ; HEAT-STRESS ; ARABIDOPSIS-THALIANA ; GENE ; THERMOTOLERANCE ; TRANSLATION ; METHYLATION ; TOLERANCE ; ENCODES ; IDENTIFICATION
WOS研究方向	Cell Biology ; Developmental Biology
WOS记录号	WOS:000531021400007
出版者	CELL PRESS
文献子类	Article
出版地	CAMBRIDGE
EISSN	1878-1551
资助机构	Basic Science Center Program of National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31788103] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31625016, 91753000]
作者邮箱	ygyang@big.ac.cn ; chongk@ibcas.ac.cn
作品OA属性	Bronze
引用统计	被引频次：71[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/21768
专题	中科院植物分子生理学重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China 2.Chinese Acad Sci, Key Lab Genom & Precis Med, Collaborat Innovat Ctr Genet & Dev, Beijing Inst Genom,Coll Future Technol, Beijing 100101, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Univ Chinese Acad Sci, Sino Danish Coll, Beijing 100049, Peoples R China 5.Chinese Acad Sci, Inst Stem Cell & Regenerat, Beijing 100101, Peoples R China 6.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 7.Chinese Acad Sci, Innovat Acad Seed Design, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Tang, Yongyan,Gao, Chun-Chun,Gao, Ying,et al. OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature[J]. DEVELOPMENTAL CELL,2020,53(3):272-296.
APA	Tang, Yongyan.,Gao, Chun-Chun.,Gao, Ying.,Yang, Ying.,Shi, Boyang.,...&Chong, Kang.(2020).OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature.DEVELOPMENTAL CELL,53(3),272-296.
MLA	Tang, Yongyan,et al."OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature".DEVELOPMENTAL CELL 53.3(2020):272-296.

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