Honokiol suppresses mycelial growth and reduces virulence of Botrytis cinerea by inducing autophagic activities and apoptosis

doi:10.1016/j.fm.2019.103411

	Honokiol suppresses mycelial growth and reduces virulence of Botrytis cinerea by inducing autophagic activities and apoptosis
	Ma, Danying 1; Cui, Xiaomin 1; Zhang, Zhanquan ; Li, Boqiang ; Xu, Yong ; Tian, Shiping1,2 ; Chen, Tong
	2020
发表期刊	FOOD MICROBIOLOGY
ISSN	0740-0020
卷号	88
摘要	Fungal pathogens lead to severe quality deterioration and yield loss, making it urgent to explore efficient measures to control fungal diseases at the preharvest and postharvest stages of plants. Therefore, studies on natural substances targeting alternative antimicrobial targets have become hot spots of research. Here, we show that honokiol, a polyphenolic compound obtained from Magnolia officinalis, significantly suppressed mycelial growth and reduced virulence of B. cinerea on harvested fruit by inducing autophagic activities and apoptosis. Moreover, honokiol was capable of abolishing the mitochondrial membrane potential and inducing the accumulation of reactive oxygen species. Some key genes involved in pathogenicity on fruit were also found significantly down-regulated. In summary, honokiol was effective as an alternative agent targeting autophagic and apoptotic machineries to control the incidence of gray mold, which may further enrich the toolkit of crop managers for fighting postharvest diseases caused by this and similar fungi.
关键词	Autophagic activity Botrytis cinerea Honokiol Reactive oxygen species
学科领域	Biotechnology & Applied Microbiology ; Food Science & Technology ; Microbiology
DOI	10.1016/j.fm.2019.103411
收录类别	SCI
语种	英语
WOS关键词	IN-VITRO ; GENE ; MECHANISM ; PRODUCT
WOS研究方向	Biotechnology & Applied Microbiology ; Food Science & Technology ; Microbiology
WOS记录号	WOS:000508555800007
出版者	ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
文献子类	Article
出版地	LONDON
EISSN	1095-9998
资助机构	National Key Research and Development Program of China [2017YFD0401301] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31930086, 30672210]
作者邮箱	chentong@ibcas.ac.cn
引用统计	被引频次：33[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/21947
专题	中科院北方资源植物重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Minist Agr, Key Lab Postharvest Handling Fruits, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Ma, Danying,Cui, Xiaomin,Zhang, Zhanquan,et al. Honokiol suppresses mycelial growth and reduces virulence of Botrytis cinerea by inducing autophagic activities and apoptosis[J]. FOOD MICROBIOLOGY,2020,88.
APA	Ma, Danying.,Cui, Xiaomin.,Zhang, Zhanquan.,Li, Boqiang.,Xu, Yong.,...&Chen, Tong.(2020).Honokiol suppresses mycelial growth and reduces virulence of Botrytis cinerea by inducing autophagic activities and apoptosis.FOOD MICROBIOLOGY,88.
MLA	Ma, Danying,et al."Honokiol suppresses mycelial growth and reduces virulence of Botrytis cinerea by inducing autophagic activities and apoptosis".FOOD MICROBIOLOGY 88(2020).

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