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| Neuropharmacological potential of various morphological parts of Camellia sinensis L. | |
| Rubab, Saima; Rizwani, Ghazala H.; Bahadur, Saraj2; Shah, Muzammil; Alsamadany, Hameed; Alzahrani, Yahya; Alghamdi, Sameera A.; Anwar, Yasir3; Shuaib, Muhammad4; Shah, Asad Ali5,7; Muhammad, Ikram6; Zaman, Wajid7,8 | |
| 2020 | |
| Source Publication | SAUDI JOURNAL OF BIOLOGICAL SCIENCES
 |
| ISSN | 1319-562X |
| Volume | 27Issue:1Pages:567-573 |
| Abstract | Camellia sinensis L. has long been used as a therapeutic agent for the Central nervous system (CNS) due to the presence of flavonoids. The present study aimed to evaluate the dose-dependent Neuropharmacological behavioral potential of Camellia sinensis seed and leaf extracts on mice. To evaluate the differential potential of leaf and seed extract various doses were prepared and examined in open field, head dip, rearing, cage cross, swimming and traction tests. One-way ANOVA set at P* < 0.05 followed by POST HOC LSD (P* < 0.01) was applied to evaluate the significant difference among the treatments. Herein both seed and leaf extract showed significant results at high doses. Interestingly leaf extract at high dose showed significant effect on mice CNS in open field and head dip test, while seed at high dose revealed significant stimulus on mice CNS in rearing, cage cross, swimming and traction tests. Overall results showed that seed produced more stimulant effect and less calmness as compared to leaf extract was. Tea leaves had already known as potential CNS stimulant drugs; current investigation suggests that tea seed can be used as an alternative CNS stimulant agent with more effective stimulant action. (C) 2019 The Author(s). Published by Elsevier B.V. on behalf of King Saud University. |
| Keyword | Camellia sinensis Therapeutic Central nervous system Pharmacological Stimulant |
| Subject Area | Biology |
| DOI | 10.1016/j.sjbs.2019.11.025 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | METHANOL EXTRACT ; DEPRESSION ; POLYPHENOLS ; MOOD |
| WOS Research Area | Life Sciences & Biomedicine - Other Topics |
| WOS ID | WOS:000503431500075 |
| Publisher | ELSEVIER |
| Subtype | Article |
| Publication Place | AMSTERDAM |
| Corresponding Author Email | saima_rubab@hotmail.com ; siraj.bahadur@bs.qau.edu.pk |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ibcas.ac.cn/handle/2S10CLM1/21963 |
| Collection | 系统与进化植物学国家重点实验室 |
| Affiliation | 1.LMDC Lahore, Lahore Pharm Coll, Dept Pharmacognosy, Lahore, Pakistan 2.Rizwani, Ghazala H.] Hamdard Univ, Hakim Shaheed Rd, Karachi, Pakistan 3.Hainan Univ, Coll Life & Pharmaceut Sci, Haikou, Hainan, Peoples R China 4.King Abdulaziz Univ, Fac Sci, Dept Biol Sci, Jeddah 21589, Saudi Arabia 5.Yunnan Univ, Sch Ecol & Environm Sci, Kunming, Yunnan, Peoples R China 6.Jazan Univ, Coll Appl Med Sci, Dept Med Lab Technol, Jizan, Saudi Arabia 7.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Lab Plant Metab Engn, Kunming, Yunnan, Peoples R China 8.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 9.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China 10.Alghamdi, Sameera A.] King Abdulazia Univ, Princess Najla Bint Al Saud Saud Ctr Excellence R, Jeddah, Saudi Arabia |
| Recommended Citation GB/T 7714 | Rubab, Saima,Rizwani, Ghazala H.,Bahadur, Saraj,et al. Neuropharmacological potential of various morphological parts of Camellia sinensis L.[J]. SAUDI JOURNAL OF BIOLOGICAL SCIENCES,2020,27(1):567-573. |
| APA | Rubab, Saima.,Rizwani, Ghazala H..,Bahadur, Saraj.,Shah, Muzammil.,Alsamadany, Hameed.,...&Zaman, Wajid.(2020).Neuropharmacological potential of various morphological parts of Camellia sinensis L..SAUDI JOURNAL OF BIOLOGICAL SCIENCES,27(1),567-573. |
| MLA | Rubab, Saima,et al."Neuropharmacological potential of various morphological parts of Camellia sinensis L.".SAUDI JOURNAL OF BIOLOGICAL SCIENCES 27.1(2020):567-573. |
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| Rubab-2020-Neurophar（794KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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