A PIF1/PIF3-HY5-BBX23 Transcription Factor Cascade Affects Photomorphogenesis

doi:10.1080/23802359.2017.1413291

IB-CAS > 中科院光生物学重点实验室

	A PIF1/PIF3-HY5-BBX23 Transcription Factor Cascade Affects Photomorphogenesis
	Zhang, Xinyu 1; Huai, Junling ; Shang, Fangfang 1; Xu, Gang 1; Tang, Weijiang ; Jing, Yanjun ; Lin, Rongcheng1
	2017
发表期刊	PLANT PHYSIOLOGY
ISSN	0032-0889
卷号	174 期号:4 页码:2487-2500
摘要	Light signaling plays an essential role in controlling higher plants' early developmental process termed as photomorphogenesis. Transcriptional regulation is a vital mechanism that is orchestrated by transcription factors and other regulatory proteins working in concert to finely tune gene expression. Although many transcription factors/regulators have been characterized in the light-signaling pathway, their interregulation remains largely unknown. Here, we show that PHYTOCHROME-INTERACTING FACTOR3 (PIF3) and PIF1 transcription factors directly bind to the regulatory regions of ELONGATED HYPOCOTYL5 (HY5) and a B-box gene BBX23 and activate their expression in Arabidopsis (Arabidopsis thaliana). We found that BBX23 and its close homolog gene BBX22 play a redundant role in regulating hypocotyl growth, and that plants overexpressing BBX23 display reduced hypocotyl elongation under red, far-red, and blue light conditions. Intriguingly, BBX23 transcription is inhibited by light, whereas its protein is degraded in darkness. Furthermore, we demonstrate that HY5 physically interacts with BBX23, and these two proteins coordinately regulate the expression of both light-induced and light-repressed genes. BBX23 is also recruited to the promoter sequences of the light-responsive genes in a partial HY5-dependent manner. Taken together, our study reveals that the transcriptional cascade consisting of PIF1/PIF3, HY5, and BBX23 controls photomorphogenesis, providing a transcriptional regulatory layer by which plants fine-tune their growth in response to changing light environment.
学科领域	Genetics & Heredity
DOI	10.1080/23802359.2017.1413291
收录类别	SCI
语种	英语
WOS关键词	B-BOX PROTEIN ; LIGHT SIGNAL-TRANSDUCTION ; ZINC-FINGER PROTEINS ; SEEDLING PHOTOMORPHOGENESIS ; MEDIATED DEGRADATION ; GENE-EXPRESSION ; COP1-MEDIATED UBIQUITINATION ; ARABIDOPSIS-THALIANA ; PLANT DEVELOPMENT ; BLUE-LIGHT
WOS记录号	WOS:000423158500245
出版者	AMER SOC PLANT BIOLOGISTS
文献子类	Article
出版地	ROCKVILLE
EISSN	1532-2548
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31325002, 31570310] ; Ministry of Agriculture of ChinaMinistry of Agriculture, China [2016ZX08009-003] ; National Key Research and Development Program of China [2017YFA0503800]
作者邮箱	rclin@ibcas.ac.cn
作品OA属性	Green Published, gold
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/22098
专题	中科院光生物学重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Photobiol, CAS Ctr Excellence Mol Plant Sci, Inst Bot, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xinyu,Huai, Junling,Shang, Fangfang,et al. A PIF1/PIF3-HY5-BBX23 Transcription Factor Cascade Affects Photomorphogenesis[J]. PLANT PHYSIOLOGY,2017,174(4):2487-2500.
APA	Zhang, Xinyu.,Huai, Junling.,Shang, Fangfang.,Xu, Gang.,Tang, Weijiang.,...&Lin, Rongcheng.(2017).A PIF1/PIF3-HY5-BBX23 Transcription Factor Cascade Affects Photomorphogenesis.PLANT PHYSIOLOGY,174(4),2487-2500.
MLA	Zhang, Xinyu,et al."A PIF1/PIF3-HY5-BBX23 Transcription Factor Cascade Affects Photomorphogenesis".PLANT PHYSIOLOGY 174.4(2017):2487-2500.

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