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Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives | |
Wu, Qiong; Han, Ting-Shen; Chen, Xi; Chen, Jia-Fu; Zou, Yu-Pan; Li, Zi-Wen; Xu, Yong-Chao; Guo, Ya-Long | |
2017 | |
发表期刊 | GENOME BIOLOGY |
ISSN | 1474-760X |
卷号 | 18 |
摘要 | Background: In contrast to positive selection, which reduces genetic variation by fixing beneficial alleles, balancing selection maintains genetic variation within a population or species and plays crucial roles in adaptation in diverse organisms. However, which genes, genome-wide, are under balancing selection and the extent to which these genes are involved in adaptation are largely unknown. Results: We performed a genome-wide scan for genes under balancing selection across two plant species, Arabidopsis thaliana and its relative Capsella rubella, which diverged about 8 million generations ago. Among hundreds of genes with shared coding-region polymorphisms, we find evidence for long-term balancing selection in five genes: AT1G35220, AT2G16570, AT4G29360, AT5G38460, and AT5G44000. These genes are involved in the response to biotic and abiotic stress and other fundamental biochemical processes. More intriguingly, for these genes, we detected significant ecological diversification between the two haplotype groups, suggesting that balancing selection has been very important for adaptation. Conclusions: Our results indicate that beyond the well-known S-locus genes and resistance genes, many loci are under balancing selection. These genes are mostly correlated with resistance to stress or other fundamental functions and likely play a more important role in adaptation to diverse habitats than previously thought. |
关键词 | Adaptation Arabidopsis thaliana Balancing selection Capsella rubella Trans-species polymorphism |
学科领域 | Plant Sciences |
DOI | 10.1093/botlinnean/box036 |
收录类别 | SCI |
语种 | 英语 |
WOS关键词 | CAPSELLA-RUBELLA ; TRANSSPECIES POLYMORPHISM ; RECENT SPECIATION ; S-LOCUS ; GENOME ; THALIANA ; EVOLUTION ; RESISTANCE ; MAINTAINS ; HISTORY |
WOS记录号 | WOS:000406943300003 |
出版者 | BMC |
文献子类 | Article |
出版地 | LONDON |
资助机构 | National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [91231104, 31222006, 31470331, 61103066] ; 100 Talents Program of the Chinese Academy of SciencesChinese Academy of Sciences |
作者邮箱 | yalong.guo@ibcas.ac.cn |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ibcas.ac.cn/handle/2S10CLM1/22285 |
专题 | 系统与进化植物学国家重点实验室 |
作者单位 | 1.[Wu, Qiong 2.Han, Ting-Shen 3.Chen, Xi 4.Chen, Jia-Fu 5.Zou, Yu-Pan 6.Li, Zi-Wen 7.Xu, Yong-Chao 8.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China 9.[Han, Ting-Shen 10.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Wu, Qiong,Han, Ting-Shen,Chen, Xi,et al. Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives[J]. GENOME BIOLOGY,2017,18. |
APA | Wu, Qiong.,Han, Ting-Shen.,Chen, Xi.,Chen, Jia-Fu.,Zou, Yu-Pan.,...&Guo, Ya-Long.(2017).Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives.GENOME BIOLOGY,18. |
MLA | Wu, Qiong,et al."Long-term balancing selection contributes to adaptation in Arabidopsis and its relatives".GENOME BIOLOGY 18(2017). |
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Zhang-2017-Molecular(3786KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 |
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