A TRIM insertion in the promoter of Ms2 causes male sterility in wheat

doi:10.1111/jipb.12553

	A TRIM insertion in the promoter of Ms2 causes male sterility in wheat
	Xia, Chuan ; Zhang, Lichao ; Zou, Cheng ; Gu, Yongqiang 1; Duan, Jialei ; Zhao, Guangyao ; Wu, Jiajie ; Liu, Yue ; Fang, Xiaohua 2; Gao, Lifeng ; Jiao, Yuannian3 ; Sun, Jiaqiang ; Pan, Yinghong ; Liu, Xu ; Jia, Jizeng ; Kong, Xiuying
	2017
发表期刊	NATURE COMMUNICATIONS
ISSN	2041-1723
卷号	8
摘要	The male-sterile ms2 mutant has been known for 40 years and has become extremely important in the commercial production of wheat. However, the gene responsible for this phenotype has remained unknown. Here we report the map-based cloning of the Ms2 gene. The Ms2 locus is remarkable in several ways that have implications in basic biology. Beyond having no functional annotation, barely detectable transcription in fertile wild-type wheat plants, and accumulated destructive mutations in Ms2 orthologs, the Ms2 allele in the ms2 mutant has acquired a terminal-repeat retrotransposon in miniature (TRIM) element in its promoter. This TRIM element is responsible for the anther-specific Ms2 activation that confers male sterility. The identification of Ms2 not only unravels the genetic basis of a historically important breeding trait, but also shows an example of how a TRIM element insertion near a gene can contribute to genetic novelty and phenotypic plasticity.
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
DOI	10.1111/jipb.12553
收录类别	SCI
语种	英语
WOS关键词	TERMINAL-REPEAT RETROTRANSPOSONS ; POLLEN DEVELOPMENT ; MINIATURE TRIM ; DRAFT GENOME ; GENE ; PROTEIN ; RICE ; EVOLUTIONARY ; ARABIDOPSIS ; ANTHER
WOS记录号	WOS:000403018500001
出版者	NATURE PUBLISHING GROUP
文献子类	Article
出版地	LONDON
资助机构	National Key Research and Development Program of China [2016YFD0100302, 2016YFD0101802] ; National Transgenic Research Project of China [2009ZX08009-110B] ; National Basic Research Program of ChinaNational Basic Research Program of China [2004CB117202, 2010CB125902] ; CAAS-Innovation Team Project
作者邮箱	jiajizeng@caas.cn ; kongxiuying@caas.cn
作品OA属性	Bronze
引用统计
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/22296
专题	系统与进化植物学国家重点实验室
作者单位	1.Chinese Acad Agr Sci, Natl Key Facil Crop Gene Resources & Genet Improv, Key Lab Crop Gene Resources & Germplasm Enhanceme, Minist Agr,Inst Crop Sci, Beijing 100081, Peoples R China 2.ARS, USDA, Western Reg Res Ctr, Albany, CA 94710 USA 3.Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Mol Dev Biol, Beijing 100101, Peoples R China 4.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Xia, Chuan,Zhang, Lichao,Zou, Cheng,et al. A TRIM insertion in the promoter of Ms2 causes male sterility in wheat[J]. NATURE COMMUNICATIONS,2017,8.
APA	Xia, Chuan.,Zhang, Lichao.,Zou, Cheng.,Gu, Yongqiang.,Duan, Jialei.,...&Kong, Xiuying.(2017).A TRIM insertion in the promoter of Ms2 causes male sterility in wheat.NATURE COMMUNICATIONS,8.
MLA	Xia, Chuan,et al."A TRIM insertion in the promoter of Ms2 causes male sterility in wheat".NATURE COMMUNICATIONS 8(2017).

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Liu-2017-Announcemen（813KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览请求全文