Evolutionary patterns of genic DNA methylation vary across land plants

doi:10.1038/NPLANTS.2015.222

	Evolutionary patterns of genic DNA methylation vary across land plants
	Takuno, Shohei ; Ran, Jin-Hua ; Gaut, Brandon S.
	2016
发表期刊	NATURE PLANTS
ISSN	2055-026X
卷号	2 期号:2
摘要	Little is known about patterns of genic DNA methylation across the plant kingdom or about the evolutionary processes that shape them. To characterize gene-body methylation (gbM) within exons, we have gathered single-base resolution methylome data that span the phylogenetic breadth of land plants. We find that a basal land plant, Marchantia polymorpha, lacks any evident signal of gbM within exons, but conifers have high levels of both CG and CHG (where H is A, C or T) methylation in expressed genes. To begin to understand the evolutionary forces that shape gbM, we first tested for correlations in methylation levels across orthologues(1,2). Genic CG methylation levels, but not CHG or CHH levels, are correlated across orthologues for species as distantly related as ferns and angiosperms. Hence, relative levels of CG methylation are a consistent property across genes, even for species that diverged similar to 400 million years ago(3,4). In contrast, genic CHG methylation correlates with genome size, suggesting that the host epigenetic response to transposable elements also affects genes. Altogether, our data indicate that the evolutionary forces acting on DNA methylation vary substantially across species, genes and methylation contexts.
学科领域	Plant Sciences
DOI	10.1038/NPLANTS.2015.222
收录类别	SCI
语种	英语
WOS关键词	CYTOSINE METHYLATION ; GENOME ; REVEALS ; EPIGENOME ; GENES ; SITES
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000375393200008
出版者	NATURE PUBLISHING GROUP
文献子类	Article
出版地	LONDON
EISSN	2055-0278
资助机构	SOKENDAI ; JSPSMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of Science [15K18585] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31330008] ; NSFNational Science Foundation (NSF) [IOS-1542703] ; Direct For Biological SciencesNational Science Foundation (NSF)NSF - Directorate for Biological Sciences (BIO) [1542703] Funding Source: National Science Foundation
作者邮箱	jinhua_ran@ibcas.ac.cn ; bgaut@uci.edu
引用统计	被引频次：144[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/25068
专题	系统与进化植物学国家重点实验室
作者单位	1.Grad Univ Adv Studies, SOKENDAI, Hayama, Kanagawa 2400193, Japan 2.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing, Peoples R China 3.Ran, Jin-Hua; Gaut, Brandon S.] Univ Calif Irvine, Dept Ecol & Evolutionary Biol, 321 Steinhaus Hall, Irvine, CA 92697 USA
推荐引用方式 GB/T 7714	Takuno, Shohei,Ran, Jin-Hua,Gaut, Brandon S.. Evolutionary patterns of genic DNA methylation vary across land plants[J]. NATURE PLANTS,2016,2(2).
APA	Takuno, Shohei,Ran, Jin-Hua,&Gaut, Brandon S..(2016).Evolutionary patterns of genic DNA methylation vary across land plants.NATURE PLANTS,2(2).
MLA	Takuno, Shohei,et al."Evolutionary patterns of genic DNA methylation vary across land plants".NATURE PLANTS 2.2(2016).

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Takuno-2016-Evolutio（611KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	浏览请求全文