Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig

doi:10.1186/s40064-016-3187-0

	Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig
	Cui, Jingxiang 1; Chen, Wei ; Liu, Jie 1; Xu, Tao 2; Zeng, Yongqing
	2016
发表期刊	SPRINGERPLUS
ISSN	2193-1801
卷号	5
摘要	Background: Intramuscular fat (intramuscular fat, IMF) is one of the important traits of pork quality. How to reasonably improve the intramuscular fat content is the most focus researchers. Some possible regulation of intramuscular fat deposition of candidate genes to cause the attention of people. The objective of this study was to elucidate the relationship between peroxisome proliferator-activated receptor. (PPAR.) and adipose differentiation-related protein (ADRP) mRNA expression and intramuscular fat (IMF) deposition in the muscle tissue of three breeds of pig: Laiwu (LW), Lulai Black (LL), and Large White (LY). Results: qPCR analysis of the PPAR. and ADRP genes in the three breeds of pig revealed PPAR. and ADRP mRNA expression profiles of LW > LL > LY and LL > LW > LY, respectively. PPAR. mRNA expression was significantly and positively correlated with IMF deposition (p < 0.05). There were significant correlations between PPAR. and ADRP mRNA expression levels (p < 0.01). Conclusions: These results suggest correlations between PPAR. and ADRP in fat deposition and regulation in pigs, PPAR. gene may be a main effector of IMF content and play an important role during adipocyte differentiation in pigs, thereby providing new information to further elucidate molecular mechanisms associated with intramuscular fat deposition in Laiwu pigs and provides new data for further molecular studies of mechanisms underlying intramuscular fat deposition in human obesity. The continued elucidation of specific genetic mechanisms between PPAR. and ADRP warrants further studies.
关键词	Pig PPAR gamma ADRP QRT-PCR Fat deposition
学科领域	Multidisciplinary Sciences
DOI	10.1186/s40064-016-3187-0
收录类别	SCI
语种	英语
WOS关键词	MOLECULAR CHARACTERIZATION ; PORCINE PREADIPOCYTES ; LONGISSIMUS-DORSI ; GENE-EXPRESSION ; MEAT QUALITY ; GAMMA ; DIFFERENTIATION ; BREEDS ; PCR ; ADIPOPHILIN
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000391798600005
出版者	SPRINGER INTERNATIONAL PUBLISHING AG
文献子类	Article
出版地	CHAM
资助机构	National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31401055] ; Shandong Province Agricultural Animal Breeding Project of China [2013LZ02-015] ; Shandong Province Modern Pig Technology and Industry System Project [SDAIT-06-022-03] ; Shandong Province Weifang city science and Technology Bureau Project of China [201301153] ; Shandong University of science and technology project [J16LE58]
作者邮箱	yqzeng@sdau.edu.cn
作品OA属性	gold, Green Published
引用统计	被引频次：24[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/25256
专题	中科院北方资源植物重点实验室
作者单位	1.Shandong Agr Univ, Coll Anim Sci & Technol, Tai An 271018, Shandong, Peoples R China 2.Weifang Univ Sci & Technol, Shouguang 262700, Shandong, Peoples R China 3.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Cui, Jingxiang,Chen, Wei,Liu, Jie,et al. Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig[J]. SPRINGERPLUS,2016,5.
APA	Cui, Jingxiang,Chen, Wei,Liu, Jie,Xu, Tao,&Zeng, Yongqing.(2016).Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig.SPRINGERPLUS,5.
MLA	Cui, Jingxiang,et al."Study on quantitative expression of PPAR. and ADRP in muscle and its association with intramuscular fat deposition of pig".SPRINGERPLUS 5(2016).

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