DEG9, a serine protease, modulates cytokinin and light signaling by regulating the level of ARABIDOPSIS RESPONSE REGULATOR 4

doi:10.1073/pnas.1601724113

IB-CAS > 中科院光生物学重点实验室

	DEG9, a serine protease, modulates cytokinin and light signaling by regulating the level of ARABIDOPSIS RESPONSE REGULATOR 4
	Chi, Wei ; Li, Jing ; He, Baoye ; Chai, Xin 1; Xu, Xiumei ; Sun, Xuwu ; Jiang, Jingjing 1; Feng, Peiqiang 1; Zuo, Jianru 2,3; Lin, Rongcheng; Rochaix, Jean-David ; Zhang, Lixin
	2016
发表期刊	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ISSN	0027-8424
卷号	113 期号:25
摘要	Cytokinin is an essential phytohormone that controls various biological processes in plants. A number of response regulators are known to be important for cytokinin signal transduction. ARABIDOPSIS RESPONSE REGULATOR 4 (ARR4) mediates the cross-talk between light and cytokinin signaling through modulation of the activity of phytochrome B. However, the mechanism that regulates the activity and stability of ARR4 is unknown. Here we identify an AT-Pindependent serine protease, degradation of periplasmic proteins 9 (DEG9), which localizes to the nucleus and regulates the stability of ARR4. Biochemical evidence shows that DEG9 interacts with ARR4, thereby targeting ARR4 for degradation, which suggests that DEG9 regulates the stability of ARR4. Moreover, genetic evidence shows that DEG9 acts upstream of ARR4 and regulates the activity of ARR4 in cytokinin and light-signaling pathways. This study thus identifies a role for a ubiquitin-independent selective protein proteolysis in the regulation of the stability of plant signaling components.
关键词	protease cytokinins light DEG ARABIDOPSIS RESPONSE REGULATOR 4
学科领域	Multidisciplinary Sciences
DOI	10.1073/pnas.1601724113
收录类别	SCI
语种	英语
WOS关键词	PHOTOSYSTEM-II ; B RESPONSE ; PHOSPHOTRANSFER PROTEINS ; 2-COMPONENT CIRCUITRY ; PROTEOMIC ANALYSIS ; PLANT PROTEASES ; GENE-EXPRESSION ; QUALITY CONTROL ; PHYTOCHROME-B ; D1 PROTEIN
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000378272400016
出版者	NATL ACAD SCIENCES
文献子类	Article
出版地	WASHINGTON
资助机构	Major State Basic Research Development ProgramNational Basic Research Program of China [2015CB150100] ; Ministry of Agriculture of ChinaMinistry of Agriculture, China [2014ZX08009-003-005] ; Key Research Program of the Chinese Academy of SciencesChinese Academy of Sciences
作者邮箱	zhanglixin@ibcas.ac.cn
作品OA属性	Green Published, Bronze
引用统计	被引频次：19[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/25309
专题	中科院光生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Photosynth Res Ctr, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Plant Genom, Beijing 100101, Peoples R China 4.Chinese Acad Sci, Inst Genet & Dev Biol, Natl Plant Gene Res Ctr, Beijing 100101, Peoples R China 5.Univ Geneva, Dept Mol Biol, CH-1211 Geneva, Switzerland 6.Univ Geneva, Dept Plant Biol, CH-1211 Geneva, Switzerland
推荐引用方式 GB/T 7714	Chi, Wei,Li, Jing,He, Baoye,et al. DEG9, a serine protease, modulates cytokinin and light signaling by regulating the level of ARABIDOPSIS RESPONSE REGULATOR 4[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2016,113(25).
APA	Chi, Wei.,Li, Jing.,He, Baoye.,Chai, Xin.,Xu, Xiumei.,...&Zhang, Lixin.(2016).DEG9, a serine protease, modulates cytokinin and light signaling by regulating the level of ARABIDOPSIS RESPONSE REGULATOR 4.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,113(25).
MLA	Chi, Wei,et al."DEG9, a serine protease, modulates cytokinin and light signaling by regulating the level of ARABIDOPSIS RESPONSE REGULATOR 4".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113.25(2016).

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