Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings

doi:10.1038/ng.3636

	Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings
	Wang, Xianglan 1; Wang, Hongwei 1; Liu, Shengxue ; Ferjani, Ali 2; Li, Jiansheng 3; Yan, Jianbing 4; Yang, Xiaohong 3; Qin, Feng
	2016
发表期刊	NATURE GENETICS
ISSN	1061-4036
卷号	48 期号:10 页码:1233-1241
摘要	Maize production is threatened by drought stress worldwide. Identification of the genetic components underlying drought tolerance in maize is of great importance. Here we report a genome-wide association study (GWAS) of maize drought tolerance at the seedling stage that identified 83 genetic variants, which were resolved to 42 candidate genes. The peak GWAS signal showed that the natural variation in ZmVPP1, encoding a vacuolar-type H+ pyrophosphatase, contributes most significantly to the trait. Further analysis showed that a 366-bp insertion in the promoter, containing three MYB cis elements, confers drought inducible expression of ZmVPP1 in drought-tolerant genotypes. Transgenic maize with enhanced ZmVPP1 expression exhibits improved drought tolerance that is most likely due to enhanced photosynthetic efficiency and root development. Taken together, this information provides important genetic insights into the natural variation of maize drought tolerance. The identified loci or genes can serve as direct targets for both genetic engineering and selection for maize trait improvement.
学科领域	Genetics & Heredity
DOI	10.1038/ng.3636
收录类别	SCI
语种	英语
WOS关键词	GENOME-WIDE ASSOCIATION ; H+-TRANSLOCATING PYROPHOSPHATASE ; QUANTITATIVE TRAIT LOCI ; ARABIDOPSIS-THALIANA ; POSTDOMESTICATION SPREAD ; TRANSPOSABLE ELEMENT ; STRESS RESPONSES ; AGRONOMIC TRAITS ; STOMATAL CLOSURE ; COLD TOLERANCE
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000384391600019
出版者	NATURE PUBLISHING GROUP
文献子类	Article
出版地	NEW YORK
EISSN	1546-1718
资助机构	National High-Tech Research and Development Program of ChinaNational High Technology Research and Development Program of China [2012AA10A306-4] ; National Basic Research Program of ChinaNational Basic Research Program of China [2012CB114302-4] ; Chinese Academy of SciencesChinese Academy of Sciences [XDA08010206] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31471505]
作者邮箱	yxiaohong@cau.edu.cn ; qinfeng@ibcas.ac.cn
引用统计	被引频次：399[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/25341
专题	中科院植物分子生理学重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China 3.Tokyo Gakugei Univ, Dept Biol, Tokyo, Japan 4.China Agr Univ, Natl Maize Improvement Ctr China, Beijing Key Lab Crop Genet Improvement, Beijing, Peoples R China 5.Huazhong Agr Univ, Natl Key Lab Crop Genet Improvement, Wuhan, Peoples R China
推荐引用方式 GB/T 7714	Wang, Xianglan,Wang, Hongwei,Liu, Shengxue,et al. Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings[J]. NATURE GENETICS,2016,48(10):1233-1241.
APA	Wang, Xianglan.,Wang, Hongwei.,Liu, Shengxue.,Ferjani, Ali.,Li, Jiansheng.,...&Qin, Feng.(2016).Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings.NATURE GENETICS,48(10),1233-1241.
MLA	Wang, Xianglan,et al."Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings".NATURE GENETICS 48.10(2016):1233-1241.

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