IB-CAS  > 中科院植物分子生理学重点实验室
Profilin Regulates Apical Actin Polymerization to Control Polarized Pollen Tube Growth
Liu, Xiaonan1; Qu, Xiaolu2,3; Jiang, Yuxiang1; Chang, Ming1; Zhang, Ruihui1; Wu, Youjun1; Fu, Ying; Huang, Shanjin1,2,4
2015
发表期刊MOLECULAR PLANT
ISSN1674-2052
卷号8期号:12页码:1694-1709
摘要Pollen tube growth is an essential step during flowering plant reproduction, whose growth depends on a population of dynamic apical actin filaments. Apical actin filaments were thought to be involved in the regulation of vesicle fusion and targeting in the pollen tube. However, the molecular mechanisms that regulate the construction of apical actin structures in the pollen tube remain largely unclear. Here, we identify profilin as an important player in the regulation of actin polymerization at the apical membrane in the pollen tube. Downregulation of profilin decreased the amount of filamentous actin and induced disorganization of apical actin filaments, and reduced tip-directed vesicle transport and accumulation in the pollen tube. Direct visualization of actin dynamics revealed that the elongation of actin filaments originating at the apical membrane decreased in profilin mutant pollen tubes. Mutant profilin that is defective in binding poly-L-proline only partially rescues the actin polymerization defect in profilin mutant pollen tubes, although it fully rescues the actin turnover phenotype. We propose that profilin controls the construction of actin structures at the pollen tube tip, presumably by favoring formin-mediated actin polymerization at the apical membrane.
关键词pollen tube actin actin polymerization profilin formin
学科领域Biochemistry & Molecular Biology ; Plant Sciences
DOI10.1016/j.molp.2015.09.013
收录类别SCI
语种英语
WOS关键词GROWING PLANT-CELLS ; TIP GROWTH ; FILAMENT ELONGATION ; LILIUM-LONGIFLORUM ; NICOTIANA-TABACUM ; ARP2/3 COMPLEX ; FH1 DOMAIN ; ADP-ACTIN ; IN-VITRO ; ARABIDOPSIS
WOS研究方向Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号WOS:000366320900002
出版者CELL PRESS
文献子类Article
出版地CAMBRIDGE
EISSN1752-9867
资助机构Ministry of Science and Technology of China [2013CB945100, 2011CB944600] ; National Natural Science Foundation of China [31125004, 31121065, 31270223] ; Tsinghua-Peking Joint Center for Life Sciences
作者邮箱sjhuang@ibcas.ac.cn
作品OA属性Bronze
引用统计
被引频次:45[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ibcas.ac.cn/handle/2S10CLM1/25652
专题中科院植物分子生理学重点实验室
作者单位1.China Agr Univ, Coll Biol Sci, State Key Lab Plant Physiol & Biochem, Beijing 100193, Peoples R China
2.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China
3.Tsinghua Univ, Sch Life Sci, Ctr Plant Biol, Beijing 100084, Peoples R China
4.Tsinghua Peking Joint Ctr Life Sci, Beijing 100084, Peoples R China
5.Natl Ctr Plant Gene Res, Beijing 100101, Peoples R China
推荐引用方式
GB/T 7714
Liu, Xiaonan,Qu, Xiaolu,Jiang, Yuxiang,et al. Profilin Regulates Apical Actin Polymerization to Control Polarized Pollen Tube Growth[J]. MOLECULAR PLANT,2015,8(12):1694-1709.
APA Liu, Xiaonan.,Qu, Xiaolu.,Jiang, Yuxiang.,Chang, Ming.,Zhang, Ruihui.,...&Huang, Shanjin.(2015).Profilin Regulates Apical Actin Polymerization to Control Polarized Pollen Tube Growth.MOLECULAR PLANT,8(12),1694-1709.
MLA Liu, Xiaonan,et al."Profilin Regulates Apical Actin Polymerization to Control Polarized Pollen Tube Growth".MOLECULAR PLANT 8.12(2015):1694-1709.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Profilin_Regulates_A(3835KB)期刊论文出版稿开放获取CC BY-NC-SA浏览 请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liu, Xiaonan]的文章
[Qu, Xiaolu]的文章
[Jiang, Yuxiang]的文章
百度学术
百度学术中相似的文章
[Liu, Xiaonan]的文章
[Qu, Xiaolu]的文章
[Jiang, Yuxiang]的文章
必应学术
必应学术中相似的文章
[Liu, Xiaonan]的文章
[Qu, Xiaolu]的文章
[Jiang, Yuxiang]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Profilin_Regulates_Apical_Actin_Polymerization.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。