The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development

doi:10.1093/jxb/erv230

	The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development
	Jia, Yuebin ; Tian, Huiyu ; Li, Hongjiang 1; Yu, Qianqian ; Wang, Lei2 ; Friml, Jiri 1; Ding, Zhaojun
	2015
发表期刊	JOURNAL OF EXPERIMENTAL BOTANY
ISSN	0022-0957
卷号	66 期号:15 页码:4631-4642
摘要	The elongator complex subunit 2 (ELP2) protein, one subunit of an evolutionarily conserved histone acetyltransferase complex, has been shown to participate in leaf patterning, plant immune and abiotic stress responses in Arabidopsis thaliana. Here, its role in root development was explored. Compared to the wild type, the elp2 mutant exhibited an accelerated differentiation of its root stem cells and cell division was more active in its quiescent centre (QC). The key transcription factors responsible for maintaining root stem cell and QC identity, such as AP2 transcription factors PLT1 (PLETHORA1) and PLT2 (PLETHORA2), GRAS transcription factors such as SCR (SCARECROW) and SHR (SHORT ROOT) and WUSCHEL-RELATED HOMEOBOX5 transcription factor WOX5, were all strongly down-regulated in the mutant. On the other hand, expression of the G2/M transition activator CYCB1 was substantially induced in elp2. The auxin efflux transporters PIN1 and PIN2 showed decreased protein levels and PIN1 also displayed mild polarity alterations in elp2, which resulted in a reduced auxin content in the root tip. Either the acetylation or methylation level of each of these genes differed between the mutant and the wild type, suggesting that the ELP2 regulation of root development involves the epigenetic modification of a range of transcription factors and other developmental regulators.
关键词	Auxin ELP2 epigenetics root
学科领域	Plant Sciences
DOI	10.1093/jxb/erv230
收录类别	SCI
语种	英语
WOS关键词	POLYMERASE-II TRANSCRIPTION ; DEPENDENT AUXIN GRADIENTS ; STEM-CELL NICHE ; HISTONE ACETYLTRANSFERASE ; PIN PHOSPHORYLATION ; DNA METHYLATION ; EFFLUX ; PROTEINS ; GENES ; DIFFERENTIATION
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000359687400017
出版者	OXFORD UNIV PRESS
文献子类	Article
出版地	OXFORD
EISSN	1460-2431
资助机构	Ministry of Science and Technology of China [2015CB942901] ; National Natural Science Foundation of China [31470371, 31270327, 31222005] ; National Natural Science Foundation of Shandong [ZR2013CQ042]
作者邮箱	dingzhaojun@sdu.edu.cn
作品OA属性	hybrid, Green Submitted, Green Published
引用统计	被引频次：30[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/25813
专题	中科院植物分子生理学重点实验室
作者单位	1.Shandong Univ, Coll Life Sci, Minist Educ, Key Lab Plant Cell Engn & Germplasm Innovat, Jinan 250100, Peoples R China 2.IST Austria, A-3400 Klosterneuburg, Austria 3.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Jia, Yuebin,Tian, Huiyu,Li, Hongjiang,et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development[J]. JOURNAL OF EXPERIMENTAL BOTANY,2015,66(15):4631-4642.
APA	Jia, Yuebin.,Tian, Huiyu.,Li, Hongjiang.,Yu, Qianqian.,Wang, Lei.,...&Ding, Zhaojun.(2015).The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development.JOURNAL OF EXPERIMENTAL BOTANY,66(15),4631-4642.
MLA	Jia, Yuebin,et al."The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development".JOURNAL OF EXPERIMENTAL BOTANY 66.15(2015):4631-4642.

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