Divergence and adaptive evolution of the gibberellin oxidase genes in plants

doi:10.1186/s12862-015-0490-2

	Divergence and adaptive evolution of the gibberellin oxidase genes in plants
	Huang, Yuan ; Wang, Xi ; Ge, Song1 ; Rao, Guang-Yuan
	2015
发表期刊	BMC EVOLUTIONARY BIOLOGY
ISSN	1471-2148
卷号	15
摘要	Background: The important phytohormone gibberellins (GAs) play key roles in various developmental processes. GA oxidases (GAoxs) are critical enzymes in GA synthesis pathway, but their classification, evolutionary history and the forces driving the evolution of plant GAox genes remain poorly understood. Results: This study provides the first large-scale evolutionary analysis of GAox genes in plants by using an extensive whole-genome dataset of 41 species, representing green algae, bryophytes, pteridophyte, and seed plants. We defined eight subfamilies under the GAox family, namely C-19-GA2ox, C-20-GA2ox, GA20ox, GA3ox, GAox-A, GAox-B, GAox-C and GAox-D. Of these, subfamilies GAox-A, GAox-B, GAox-C and GAox-D are described for the first time. On the basis of phylogenetic analyses and characteristic motifs of GAox genes, we demonstrated a rapid expansion and functional divergence of the GAox genes during the diversification of land plants. We also detected the subfamily-specific motifs and potential sites of some GAox genes, which might have evolved under positive selection. Conclusions: GAox genes originated very early-before the divergence of bryophytes and the vascular plants and the diversification of GAox genes is associated with the functional divergence and could be driven by positive selection. Our study not only provides information on the classification of GAox genes, but also facilitates the further functional characterization and analysis of GA oxidases.
关键词	Characteristic motif Functional divergence Gibberellin Phytohormones Positive selection 2-oxoglutarate-dependent dioxygenase
学科领域	Evolutionary Biology ; Genetics & Heredity
DOI	10.1186/s12862-015-0490-2
收录类别	SCI
语种	英语
WOS关键词	DETECTING MOLECULAR ADAPTATION ; MULTIPLE SEQUENCE ALIGNMENT ; CODON-SUBSTITUTION MODELS ; AMINO-ACID SITES ; POSITIVE SELECTION ; SECONDARY METABOLISM ; MAXIMUM-LIKELIHOOD ; DUPLICATE GENES ; FUNCTIONAL-CHARACTERIZATION ; PHYSCOMITRELLA-PATENS
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000361811600001
出版者	BIOMED CENTRAL LTD
文献子类	Article
出版地	LONDON
资助机构	National Natural Science Foundation of China [30990240]
作者邮箱	rao@pku.edu.cn
作品OA属性	Green Published, gold
引用统计	被引频次：45[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/26000
专题	系统与进化植物学国家重点实验室
作者单位	1.Peking Univ, Coll Life Sci, Beijing 100871, Peoples R China 2.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Huang, Yuan,Wang, Xi,Ge, Song,et al. Divergence and adaptive evolution of the gibberellin oxidase genes in plants[J]. BMC EVOLUTIONARY BIOLOGY,2015,15.
APA	Huang, Yuan,Wang, Xi,Ge, Song,&Rao, Guang-Yuan.(2015).Divergence and adaptive evolution of the gibberellin oxidase genes in plants.BMC EVOLUTIONARY BIOLOGY,15.
MLA	Huang, Yuan,et al."Divergence and adaptive evolution of the gibberellin oxidase genes in plants".BMC EVOLUTIONARY BIOLOGY 15(2015).

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