Functional Divergence of the Glutamine Phosphoribosyl Pyrophosphate Amidotransferase (ASE) Gene Family in Arabidopsis

doi:10.1134/S0022093021060119

	Functional Divergence of the Glutamine Phosphoribosyl Pyrophosphate Amidotransferase (ASE) Gene Family in Arabidopsis
	Liu, Hai-Jing ; Yang, Zhi-Ling ; Ren, Lin-Ling ; Wang, Yi-Ming ; Wang, Xin ; Qian, Ting-Ting
	2021
发表期刊	JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY
ISSN	0022-0930
卷号	57 期号:6 页码:1310-1321
摘要	Background: Functional divergence occurs widely among duplicated genes in plants. The divergence of functional genes may result from changes in gene regulation or protein-coding regions, or both. These changes contributing to the functional divergence of plants require further elucidation. Glutamine phosphoribosyl pyrophosphate amidotransferase (ASE) is a key enzyme in de novo purine biosynthesis and plays important roles in plant growth and development. Results: In our research, three ASE genes were identified in the Arabidopsis thaliana genome, and they were designated AtASE1, AtASE2 and AtASE3. Gene expression profiles revealed that the three genes exhibit very different expression, and gene regulation plays a pivotal role in the divergence of the ASE gene family. Subcellular localization analysis indicated that the three proteins were all localized in chloroplasts. Protein biochemical analysis revealed that the catalytic abilities of ASE proteins show differentiation, but further transgenic overexpression experiments proved that this was not the main reason for physiological functional divergence. Conclusions: Our results indicate that the functional divergence of the ASE gene family members might result from changes in their promoters, but not protein-coding region.
关键词	functional divergence glutamine phosphoribosyl pyrophosphate amidotransferase gene regulation protein-coding region Arabidopsis thaliana
学科领域	Biochemistry & Molecular Biology ; Evolutionary Biology ; Physiology
DOI	10.1134/S0022093021060119
收录类别	SCI
语种	英语
WOS关键词	NUCLEOTIDE-SEQUENCE ; ESCHERICHIA-COLI ; SUPERGENE FAMILY ; DUPLICATED GENES ; EXPRESSION ; EVOLUTION ; CLONING ; NITROGEN ; ENZYME ; DEATH
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000732957200011
出版者	PLEIADES PUBLISHING INC
文献子类	Article
出版地	NEW YORK
EISSN	1608-3202
资助机构	National Natural Science Foundation of China [31400574] ; High-Level Talent Research Program of Inner Mongolia University [21400-5175163]
作者邮箱	liuhj@imu.edu.cn ; qiantingting.08@163.com
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/26333
专题	系统与进化植物学国家重点实验室
作者单位	1.Inner Mongolia Univ, Sch Life Sci, Key Lab Herbage & Endem Crop Biol, Minist Educ, Hohhot 010020, Peoples R China 2.[Liu, Hai-Jing 3.Yang, Zhi-Ling 4.Wang, Xin 5.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China 6.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 7.Yunnan Agr Univ, Coll Agron & Biotechnol, Kunming 650201, Yunnan, Peoples R China 8.Novogene Bioinformat Inst, Beijing 100015, Peoples R China
推荐引用方式 GB/T 7714	Liu, Hai-Jing,Yang, Zhi-Ling,Ren, Lin-Ling,et al. Functional Divergence of the Glutamine Phosphoribosyl Pyrophosphate Amidotransferase (ASE) Gene Family in Arabidopsis[J]. JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY,2021,57(6):1310-1321.
APA	Liu, Hai-Jing,Yang, Zhi-Ling,Ren, Lin-Ling,Wang, Yi-Ming,Wang, Xin,&Qian, Ting-Ting.(2021).Functional Divergence of the Glutamine Phosphoribosyl Pyrophosphate Amidotransferase (ASE) Gene Family in Arabidopsis.JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY,57(6),1310-1321.
MLA	Liu, Hai-Jing,et al."Functional Divergence of the Glutamine Phosphoribosyl Pyrophosphate Amidotransferase (ASE) Gene Family in Arabidopsis".JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY 57.6(2021):1310-1321.

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