Catabolism of strigolactones by a carboxylesterase

doi:10.1038/s41477-021-01011-y

	Catabolism of strigolactones by a carboxylesterase
	Xu, Enjun ; Chai, Liang 1; Zhang, Shiqi 1; Yu, Ruixue 1; Zhang, Xixi 3; Xu, Chongyi ; Hu, Yuxin2
	2021
发表期刊	NATURE PLANTS
ISSN	2055-026X
卷号	7 期号:11 页码:1495-1504
摘要	Strigolactones (SLs) are carotenoid-derived plant hormones that control shoot branching and communications between host plants and symbiotic fungi or root parasitic plants. Extensive studies have identified the key components participating in SL biosynthesis and signalling, whereas the catabolism or deactivation of endogenous SLs in planta remains largely unknown. Here, we report that the Arabidopsis carboxylesterase 15 (AtCXE15) and its orthologues function as efficient hydrolases of SLs. We show that overexpression of AtCXE15 promotes shoot branching by dampening SL-inhibited axillary bud outgrowth. We further demonstrate that AtCXE15 could bind and efficiently hydrolyse SLs both in vitro and in planta. We also provide evidence that AtCXE15 is capable of catalysing hydrolysis of diverse SL analogues and that such CXE15-dependent catabolism of SLs is evolutionarily conserved in seed plants. These results disclose a catalytic mechanism underlying homoeostatic regulation of SLs in plants, which also provides a rational approach to spatial-temporally manipulate the endogenous SLs and thus architecture of crops and ornamental plants. Strigolactones (SLs) play a vital role in controlling plant shoot branching. A carboxylesterase and its orthologues were identified to be efficient hydrolases of SLs, which discloses a catabolic mechanism behind homoeostasis of SLs in seed plants.
学科领域	Plant Sciences
DOI	10.1038/s41477-021-01011-y
收录类别	SCI
语种	英语
WOS关键词	SHOOT DEVELOPMENT ; ACTS DOWNSTREAM ; ARABIDOPSIS ; GENES ; RESPONSES ; RECEPTOR ; KARRIKIN ; DWARF14 ; FAMILY ; PEA
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000717408000002
出版者	NATURE PORTFOLIO
文献子类	Article
出版地	BERLIN
EISSN	2055-0278
资助机构	Strategic Priority Research Program of Chinese Academy of Sciences [XDB27030102] ; National Natural Science Foundation of China [31700253, 31830055]
作者邮箱	huyuxin@ibcas.ac.cn
引用统计	被引频次：14[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/26554
专题	中科院植物分子生理学重点实验室
作者单位	1.Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Natl Ctr Plant Gene Res, Beijing, Peoples R China 4.IST Austria, Klosterneuburg, Austria
推荐引用方式 GB/T 7714	Xu, Enjun,Chai, Liang,Zhang, Shiqi,et al. Catabolism of strigolactones by a carboxylesterase[J]. NATURE PLANTS,2021,7(11):1495-1504.
APA	Xu, Enjun.,Chai, Liang.,Zhang, Shiqi.,Yu, Ruixue.,Zhang, Xixi.,...&Hu, Yuxin.(2021).Catabolism of strigolactones by a carboxylesterase.NATURE PLANTS,7(11),1495-1504.
MLA	Xu, Enjun,et al."Catabolism of strigolactones by a carboxylesterase".NATURE PLANTS 7.11(2021):1495-1504.

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