An-1 Encodes a Basic Helix-Loop-Helix Protein That Regulates Awn Development, Grain Size, and Grain Number in Rice

doi:10.1105/tpc.113.113589

	An-1 Encodes a Basic Helix-Loop-Helix Protein That Regulates Awn Development, Grain Size, and Grain Number in Rice
	Luo, Jianghong ; Liu, Hui ; Zhou, Taoying ; Gu, Benguo ; Huang, Xuehui ; Shangguan, Yingying ; Zhu, Jingjie ; Li, Yan ; Zhao, Yan ; Wang, Yongchun ; Zhao, Qiang ; Wang, Ahong ; Wang, Ziqun ; Sang, Tao1 ; Wang, Zixuan 2; Han, Bin
	2013
发表期刊	PLANT CELL
ISSN	1040-4651
卷号	25 期号:9 页码:3360-3376
摘要	Long awns are important for seed dispersal in wild rice (Oryza rufipogon), but are absent in cultivated rice (Oryza sativa). The genetic mechanism involved in loss-of-awn in cultivated rice remains unknown. We report here the molecular cloning of a major quantitative trait locus, An-1, which regulates long awn formation in O. rufipogon. An-1 encodes a basic helix-loophelix protein, which regulates cell division. The nearly-isogenic line (NIL-An-1) carrying a wild allele An-1 in the genetic background of the awnless indica Guangluai4 produces long awns and longer grains, but significantly fewer grains per panicle compared with Guangluai4. Transgenic studies confirmed that An-1 positively regulates awn elongation, but negatively regulates grain number per panicle. Genetic variations in the An-1 locus were found to be associated with awn loss in cultivated rice. Population genetic analysis of wild and cultivated rice showed a significant reduction in nucleotide diversity of the An-1 locus in rice cultivars, suggesting that the An-1 locus was a major target for artificial selection. Thus, we propose that awn loss was favored and strongly selected by humans, as genetic variations at the An-1 locus that cause awn loss would increase grain numbers and subsequently improve grain yield in cultivated rice.
学科领域	Biochemistry & Molecular Biology ; Plant Sciences ; Cell Biology
DOI	10.1105/tpc.113.113589
收录类别	SCI
语种	英语
WOS关键词	TRANSCRIPTION FACTOR ; GENETIC-CONTROL ; PLANT DEVELOPMENT ; ARABIDOPSIS ; CYTOKININ ; GROWTH ; DOMESTICATION ; SPATULA ; DIFFERENTIATION ; ELONGATION
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000326287100018
出版者	OXFORD UNIV PRESS INC
文献子类	Article
出版地	CARY
EISSN	1532-298X
资助机构	Ministry of Science and Technology of China(Ministry of Science and Technology, China) ; Ministry of Agriculture of China(Ministry of Agriculture & Rural Affairs) ; National Natural Science Foundation of China(National Natural Science Foundation of China (NSFC))
作者邮箱	luo, jianghong/HJH-1936-2023
作品OA属性	Green Accepted
引用统计	被引频次：175[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/28032
专题	系统与进化植物学国家重点实验室
作者单位	1.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Plant Physiol & Ecol, Natl Ctr Gene Res, Shanghai 200233, Peoples R China 2.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China 3.Natl Inst Genet, Mishima, Shizuoka 4118540, Japan
推荐引用方式 GB/T 7714	Luo, Jianghong,Liu, Hui,Zhou, Taoying,et al. An-1 Encodes a Basic Helix-Loop-Helix Protein That Regulates Awn Development, Grain Size, and Grain Number in Rice[J]. PLANT CELL,2013,25(9):3360-3376.
APA	Luo, Jianghong.,Liu, Hui.,Zhou, Taoying.,Gu, Benguo.,Huang, Xuehui.,...&Han, Bin.(2013).An-1 Encodes a Basic Helix-Loop-Helix Protein That Regulates Awn Development, Grain Size, and Grain Number in Rice.PLANT CELL,25(9),3360-3376.
MLA	Luo, Jianghong,et al."An-1 Encodes a Basic Helix-Loop-Helix Protein That Regulates Awn Development, Grain Size, and Grain Number in Rice".PLANT CELL 25.9(2013):3360-3376.

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