Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia

doi:10.1073/pnas.1213962110

	Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia
	Wu, Weixun ; Zheng, Xiao-Ming ; Lu, Guangwen ; Zhong, Zhengzheng ; Gao, He ; Chen, Liping ; Wu, Chuanyin ; Wang, Hong-Jun ; Wang, Qi ; Zhou, Kunneng ; Wang, Jiu-Lin ; Wu, Fuqing 1; Zhang, Xin 1; Guo, Xiuping 1; Cheng, Zhijun 1; Lei, Cailin 1; Lin, Qibing 1; Jiang, Ling ; Wang, Haiyang 1; Ge, Song2 ; Wan, Jianmin 1
	2013
发表期刊	PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ISSN	0027-8424
卷号	110 期号:8 页码:2775-2780
摘要	Flowering time (i.e., heading date in crops) is an important ecological trait that determines growing seasons and regional adaptability of plants to specific natural environments. Rice (Oryza sativa L.) is a short-day plant that originated in the tropics. Increasing evidence suggests that the northward expansion of cultivated rice was accompanied by human selection of the heading date under noninductive long-day (LD) conditions. We report here the molecular cloning and characterization of DTH2 (for Days to heading on chromosome 2), a minor-effect quantitative trait locus that promotes heading under LD conditions. We show that DTH2 encodes a CONSTANS-like protein that promotes heading by inducing the florigen genes Heading date 3a and RICE FLOWERING LOCUS T 1, and it acts independently of the known floral integrators Heading date 1 and Early heading date 1. Moreover, association analysis and transgenic experiments identified two functional nucleotide polymorphisms in DTH2 that correlated with early heading and increased reproductive fitness under natural LD conditions in northern Asia. Our combined population genetics and network analyses suggest that DTH2 likely represents a target of human selection for adaptation to LD conditions during rice domestication and/or improvement, demonstrating an important role of minor-effect quantitative trait loci in crop adaptation and breeding.
学科领域	Multidisciplinary Sciences
DOI	10.1073/pnas.1213962110
收录类别	SCI
语种	英语
WOS关键词	FLOWERING TIME GENE ; BARLEY HORDEUM-VULGARE ; CONSTANS-LIKE GENE ; ARABIDOPSIS-THALIANA ; ARTIFICIAL SELECTION ; LATITUDINAL CLINE ; HEADING DATE ; DOMESTICATION ; WHEAT ; VERNALIZATION
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000315954400042
出版者	NATL ACAD SCIENCES
文献子类	Article
出版地	WASHINGTON
资助机构	National Natural Science Foundation of China(National Natural Science Foundation of China (NSFC)) ; Ministry of Agriculture of China(Ministry of Agriculture & Rural Affairs) ; Doctoral Foundation of Education Development of China
作者邮箱	Lin, Qibing/AAG-3882-2021 ; Cheng, Zhijun/HDN-7780-2022 ; Wu, Weixun/GPT-1875-2022
作品OA属性	Green Published, Green Accepted
引用统计	被引频次：159[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/28059
专题	系统与进化植物学国家重点实验室
作者单位	1.Nanjing Agr Univ, Jiangsu Plant Gene Engn Res Ctr, Natl Key Lab Crop Genet & Germplasm Enhancement, Nanjing 210095, Jiangsu, Peoples R China 2.Chinese Acad Agr Sci, Inst Crop Sci, Natl Key Facil Crop Gene Resources & Genet Improv, Beijing 100081, Peoples R China 3.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Wu, Weixun,Zheng, Xiao-Ming,Lu, Guangwen,et al. Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2013,110(8):2775-2780.
APA	Wu, Weixun.,Zheng, Xiao-Ming.,Lu, Guangwen.,Zhong, Zhengzheng.,Gao, He.,...&Wan, Jianmin.(2013).Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,110(8),2775-2780.
MLA	Wu, Weixun,et al."Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110.8(2013):2775-2780.

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