Antagonistic Basic Helix-Loop-Helix/bZIP Transcription Factors Form Transcriptional Modules That Integrate Light and Reactive Oxygen Species Signaling in Arabidopsis

doi:10.1105/tpc.112.104869

IB-CAS > 中科院光生物学重点实验室

	Antagonistic Basic Helix-Loop-Helix/bZIP Transcription Factors Form Transcriptional Modules That Integrate Light and Reactive Oxygen Species Signaling in Arabidopsis
	Chen, Dongqin 1; Xu, Gang 1; Tang, Weijiang ; Jing, Yanjun ; Ji, Qiang 1; Fei, Zhangjun 2; Lin, Rongcheng
	2013
发表期刊	PLANT CELL
ISSN	1040-4651
卷号	25 期号:5 页码:1657-1673
摘要	The critical developmental switch from heterotrophic to autotrophic growth of plants involves light signaling transduction and the production of reactive oxygen species (ROS). ROS function as signaling molecules that regulate multiple developmental processes, including cell death. However, the relationship between light and ROS signaling remains unclear. Here, we identify transcriptional modules composed of the basic helix-loop-helix and bZIP transcription factors PHYTOCHROME-INTERACTING FACTOR1 (PIF1), PIF3, ELONGATED HYPOCOTYL5 (HY5), and HY5 HOMOLOGY (HYH) that bridge light and ROS signaling to regulate cell death and photooxidative response. We show that pif mutants release more singlet oxygen and exhibit more extensive cell death than the wild type during Arabidopsis thaliana deetiolation. Genome-wide expression profiling indicates that PIF1 represses numerous ROS and stress-related genes. Molecular and biochemical analyses reveal that PIF1/PIF3 and HY5/HYH physically interact and coordinately regulate the expression of five ROS-responsive genes by directly binding to their promoters. Furthermore, PIF1/PIF3 and HY5/HYH function antagonistically during the seedling greening process. In addition, phytochromes, cryptochromes, and CONSTITUTIVE PHOTOMORPHOGENIC1 act upstream to regulate ROS signaling. Together, this study reveals that the PIF1/PIF3-HY5/HYH transcriptional modules mediate crosstalk between light and ROS signaling and sheds light on a new mechanism by which plants adapt to the light environments.
学科领域	Biochemistry & Molecular Biology ; Plant Sciences ; Cell Biology
DOI	10.1105/tpc.112.104869
收录类别	SCI
语种	英语
WOS关键词	PROGRAMMED CELL-DEATH ; PHYTOCHROME INTERACTING FACTOR-3 ; GENOME-WIDE ANALYSIS ; SINGLET OXYGEN ; CHLOROPHYLL BIOSYNTHESIS ; GENE-EXPRESSION ; STRESS RESPONSES ; FACTOR HY5 ; CHLOROPLAST DEVELOPMENT ; MEDIATED DEGRADATION
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000321035800016
出版者	AMER SOC PLANT BIOLOGISTS
文献子类	Article
出版地	ROCKVILLE
EISSN	1532-298X
资助机构	National Natural Science Foundation of China(National Natural Science Foundation of China (NSFC)) ; State Basic Research Development Program ; Solar Energy Initiative of the Chinese Academy of Sciences(Chinese Academy of Sciences) ; Ministry of Agriculture of China(Ministry of Agriculture & Rural Affairs)
作者邮箱	Xu, Gang/HNI-9325-2023 ; Fei, Zhangjun/H-5152-2012 ; Lin, Rongcheng/I-8105-2014
作品OA属性	Green Published
引用统计	被引频次：167[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/28127
专题	中科院光生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Cornell Univ, Boyce Thompson Inst Plant Res, Ithaca, NY 14853 USA
推荐引用方式 GB/T 7714	Chen, Dongqin,Xu, Gang,Tang, Weijiang,et al. Antagonistic Basic Helix-Loop-Helix/bZIP Transcription Factors Form Transcriptional Modules That Integrate Light and Reactive Oxygen Species Signaling in Arabidopsis[J]. PLANT CELL,2013,25(5):1657-1673.
APA	Chen, Dongqin.,Xu, Gang.,Tang, Weijiang.,Jing, Yanjun.,Ji, Qiang.,...&Lin, Rongcheng.(2013).Antagonistic Basic Helix-Loop-Helix/bZIP Transcription Factors Form Transcriptional Modules That Integrate Light and Reactive Oxygen Species Signaling in Arabidopsis.PLANT CELL,25(5),1657-1673.
MLA	Chen, Dongqin,et al."Antagonistic Basic Helix-Loop-Helix/bZIP Transcription Factors Form Transcriptional Modules That Integrate Light and Reactive Oxygen Species Signaling in Arabidopsis".PLANT CELL 25.5(2013):1657-1673.

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