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| Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering | |
Hu, Zhi1; Yang, Zhipan; Zhang, Yi2; Zhang, Aihong2; Lu, Qingtao ; Fang, Ying2; Lu, Congming2
| |
| 2022 | |
| Source Publication | MOLECULAR PLANT
 |
| ISSN | 1674-2052 |
| Volume | 15Issue:7Pages:1137-1156 |
| Abstract | Flowering time (heading date) is a critical agronomic trait that determines the yield and regional adaptability of crops. Heading date 1 (Hd1) is a central regulator of photoperiodic flowering in rice (Oryza sativa). Howev-er, how the homeostasis of Hd1 protein is achieved is poorly understood. Here, we report that the nuclear autophagy pathway mediates Hd1 degradation in the dark to regulate flowering. Loss of autophagy function results in an accumulation of Hd1 and delays flowering under both short-day and long-day conditions. In the dark, nucleus-localized Hd1 is recognized as a substrate for autophagy and is subjected to vacuolar degra-dation via the autophagy protein OsATG8. The Hd1-OsATG8 interaction is required for autophagic degrada-tion of Hd1 in the dark. Our study reveals a new mechanism by which Hd1 protein homeostasis is regulated by autophagy to control rice flowering. Our study also indicates that the regulation of flowering by autophagic degradation of Hd1 orthologs may have arisen over the course of mesangiosperm evolution, which would have increased their flexibility and adaptability to the environment by modulating flowering time. |
| Keyword | autophagy heading date rice Hd1 homeostasis |
| Subject Area | Biochemistry & Molecular Biology ; Plant Sciences |
| DOI | 10.1016/j.molp.2022.05.006 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Keyword | SELECTIVE AUTOPHAGY ; PLANT-GROWTH ; LIR MOTIF ; CONSTANS ; TIME ; PROTEINS ; HD3A ; DEGRADES ; SYSTEM ; COP1 |
| WOS Research Area | Science Citation Index Expanded (SCI-EXPANDED) |
| WOS ID | WOS:000824510600010 |
| Publisher | CELL PRESS |
| Subtype | Article |
| Publication Place | CAMBRIDGE |
| EISSN | 1752-9867 |
| Funding Organization | National Key Research and Development Program of China [2020YFA0907602] ; National Natural Science Foundation of China [31730102] |
| Corresponding Author Email | cmlu@sdau.edu.CN |
| OA | hybrid |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ibcas.ac.cn/handle/2S10CLM1/28478 |
| Collection | 中科院光生物学重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Shandong Agr Univ, Coll Life Sci, State Key Lab Crop Biol, Tai An 271018, Shandong, Peoples R China |
| Recommended Citation GB/T 7714 | Hu, Zhi,Yang, Zhipan,Zhang, Yi,et al. Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering[J]. MOLECULAR PLANT,2022,15(7):1137-1156. |
| APA | Hu, Zhi.,Yang, Zhipan.,Zhang, Yi.,Zhang, Aihong.,Lu, Qingtao.,...&Lu, Congming.(2022).Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering.MOLECULAR PLANT,15(7),1137-1156. |
| MLA | Hu, Zhi,et al."Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering".MOLECULAR PLANT 15.7(2022):1137-1156. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Autophagy_targets_Hd（4836KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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