Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering

doi:10.1016/j.molp.2022.05.006

IB-CAS > 中科院光生物学重点实验室

	Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering
	Hu, Zhi 1; Yang, Zhipan ; Zhang, Yi 2; Zhang, Aihong 2; Lu, Qingtao; Fang, Ying 2; Lu, Congming 2
	2022
发表期刊	MOLECULAR PLANT
ISSN	1674-2052
卷号	15 期号:7 页码:1137-1156
摘要	Flowering time (heading date) is a critical agronomic trait that determines the yield and regional adaptability of crops. Heading date 1 (Hd1) is a central regulator of photoperiodic flowering in rice (Oryza sativa). Howev-er, how the homeostasis of Hd1 protein is achieved is poorly understood. Here, we report that the nuclear autophagy pathway mediates Hd1 degradation in the dark to regulate flowering. Loss of autophagy function results in an accumulation of Hd1 and delays flowering under both short-day and long-day conditions. In the dark, nucleus-localized Hd1 is recognized as a substrate for autophagy and is subjected to vacuolar degra-dation via the autophagy protein OsATG8. The Hd1-OsATG8 interaction is required for autophagic degrada-tion of Hd1 in the dark. Our study reveals a new mechanism by which Hd1 protein homeostasis is regulated by autophagy to control rice flowering. Our study also indicates that the regulation of flowering by autophagic degradation of Hd1 orthologs may have arisen over the course of mesangiosperm evolution, which would have increased their flexibility and adaptability to the environment by modulating flowering time.
关键词	autophagy heading date rice Hd1 homeostasis
学科领域	Biochemistry & Molecular Biology ; Plant Sciences
DOI	10.1016/j.molp.2022.05.006
收录类别	SCI
语种	英语
WOS关键词	SELECTIVE AUTOPHAGY ; PLANT-GROWTH ; LIR MOTIF ; CONSTANS ; TIME ; PROTEINS ; HD3A ; DEGRADES ; SYSTEM ; COP1
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000824510600010
出版者	CELL PRESS
文献子类	Article
出版地	CAMBRIDGE
EISSN	1752-9867
资助机构	National Key Research and Development Program of China [2020YFA0907602] ; National Natural Science Foundation of China [31730102]
作者邮箱	cmlu@sdau.edu.CN
作品OA属性	hybrid
引用统计	被引频次：19[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/28478
专题	中科院光生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Shandong Agr Univ, Coll Life Sci, State Key Lab Crop Biol, Tai An 271018, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Hu, Zhi,Yang, Zhipan,Zhang, Yi,et al. Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering[J]. MOLECULAR PLANT,2022,15(7):1137-1156.
APA	Hu, Zhi.,Yang, Zhipan.,Zhang, Yi.,Zhang, Aihong.,Lu, Qingtao.,...&Lu, Congming.(2022).Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering.MOLECULAR PLANT,15(7),1137-1156.
MLA	Hu, Zhi,et al."Autophagy targets Hd1 for vacuolar degradation to regulate rice flowering".MOLECULAR PLANT 15.7(2022):1137-1156.

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