m6A-mediated regulation of crop development and stress responses

doi:10.1111/pbi.13792

	m6A-mediated regulation of crop development and stress responses
	Zhou, Leilei 1; Gao, Guangtong 1; Tang, Renkun 1; Wang, Weihao 1; Wang, Yuying 1; Tian, Shiping1 ; Qin, Guozheng1
	2022
发表期刊	PLANT BIOTECHNOLOGY JOURNAL
ISSN	1467-7644
卷号	20 期号:8 页码:1447-1455
摘要	Dynamic chemical modifications in eukaryotic messenger RNAs (mRNAs) constitute an essential layer of gene regulation, among which N-6-methyladenosine (m(6)A) was unveiled to be the most abundant. m(6)A functionally modulates important biological processes in various mammals and plants through the regulation of mRNA metabolism, mainly mRNA degradation and translation efficiency. Physiological functions of m(6)A methylation are diversified and affected by intricate sequence contexts and m(6)A machineries. A number of studies have dissected the functional roles and the underlying mechanisms of m(6)A modifications in regulating plant development and stress responses. Recently, it was demonstrated that the human FTO-mediated plant m(6)A removal caused dramatic yield increases in rice and potato, indicating that modulation of m(6)A methylation could be an efficient strategy for crop improvement. In this review, we summarize the current progress concerning the m(6)A-mediated regulation of crop development and stress responses, and provide an outlook on the potential application of m(6)A epitranscriptome in the future improvement of crops.
关键词	N-6-methyladenosine m(6)A machineries crop development stress responses crop improvement
学科领域	Biotechnology & Applied Microbiology ; Plant Sciences
DOI	10.1111/pbi.13792
收录类别	SCI
语种	英语
WOS关键词	MESSENGER-RNA METHYLATION ; NUCLEAR-RNA ; M(6)A METHYLATION ; CELL FATE ; N6-METHYLADENOSINE ; DEMETHYLASE ; POLYADENYLATION ; TRANSCRIPTOME ; RECOGNITION ; TRANSLATION
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000761951700001
出版者	WILEY
文献子类	Review
出版地	HOBOKEN
EISSN	1467-7652
资助机构	National Natural Science Foundation of China [31925035, 31871855] ; National Key Research and Development Program [2018YFD1000200]
作者邮箱	gzqin@ibcas.ac.cn
作品OA属性	gold, Green Published
引用统计	被引频次：29[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/28503
专题	中科院北方资源植物重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Key Lab Plant Resources, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Leilei,Gao, Guangtong,Tang, Renkun,et al. m6A-mediated regulation of crop development and stress responses[J]. PLANT BIOTECHNOLOGY JOURNAL,2022,20(8):1447-1455.
APA	Zhou, Leilei.,Gao, Guangtong.,Tang, Renkun.,Wang, Weihao.,Wang, Yuying.,...&Qin, Guozheng.(2022).m6A-mediated regulation of crop development and stress responses.PLANT BIOTECHNOLOGY JOURNAL,20(8),1447-1455.
MLA	Zhou, Leilei,et al."m6A-mediated regulation of crop development and stress responses".PLANT BIOTECHNOLOGY JOURNAL 20.8(2022):1447-1455.

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