Mutual upregulation of HY5 and TZP in mediating phytochrome A signaling

doi:10.1093/plcell/koab254

IB-CAS > 中科院光生物学重点实验室

	Mutual upregulation of HY5 and TZP in mediating phytochrome A signaling
	Li, Cong ; Qi, Lijuan ; Zhang, Shaoman ; Dong, Xiaojing ; Jing, Yanjun 1; Cheng, Jinkui ; Feng, Ziyi ; Peng, Jing ; Li, Hong ; Zhou, Yangyang ; Wang, Xiaoji ; Han, Run ; Duan, Jie ; Terzaghi, William 2; Lin, Rongcheng1 ; Li, Jigang
	2022
发表期刊	PLANT CELL
ISSN	1040-4651
卷号	34 期号:1 页码:633-654
摘要	Phytochrome A (phyA) is the far-red (FR) light photoreceptor in plants that is essential for seedling de-etiolation under FR-rich environments, such as canopy shade. TANDEM ZINC-FINGER/PLUS3 (TZP) was recently identified as a key component of phyA signal transduction in Arabidopsis thaliana; however, how TZP is integrated into the phyA signaling networks remains largely obscure. Here, we demonstrate that ELONGATED HYPOCOTYL5 (HY5), a well-characterized transcription factor promoting photomorphogenesis, mediates FR light induction of TZP expression by directly binding to a G-box motif in the TZP promoter. Furthermore, TZP physically interacts with CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1), an E3 ubiquitin ligase targeting HY5 for 26S proteasome-mediated degradation, and this interaction inhibits COP1 interaction with HY5. Consistent with those results, TZP post-translationally promotes HY5 protein stability in FR light, and in turn, TZP protein itself is destabilized by COP1 in both dark and FR light conditions. Moreover, tzp hy5 double mutants display an additive phenotype relative to their respective single mutants under high FR light intensities, indicating that TZP and HY5 also function in largely independent pathways. Together, our data demonstrate that HY5 and TZP mutually upregulate each other in transmitting the FR light signal, thus providing insights into the complicated but delicate control of phyA signaling networks.
学科领域	Biochemistry & Molecular Biology ; Plant Sciences ; Cell Biology
DOI	10.1093/plcell/koab254
收录类别	SCI
语种	英语
WOS关键词	LIGHT-DEPENDENT INTERACTION ; TRANSCRIPTION FACTOR HY5 ; COP1 E3 LIGASE ; FAR-RED LIGHT ; NUCLEAR ACCUMULATION ; INTERACTING FACTOR ; ARABIDOPSIS FHY3 ; SHADE AVOIDANCE ; GENE-EXPRESSION ; CRYPTOCHROME 1
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000745840600038
出版者	OXFORD UNIV PRESS INC
文献子类	Article
出版地	CARY
EISSN	1532-298X
资助机构	National Natural Science Foundation of China [31970262, 31770321, 32000187] ; China National Postdoctoral Program for Innovative Talents [BX20200371] ; China Postdoctoral Science Foundation [2020M670531, 2021M693432] ; Chinese Universities Scientific Fund [2021TC064] ; Beijing Outstanding University Discipline Program
作者邮箱	jigangli@cau.edu.cn
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/28643
专题	中科院光生物学重点实验室
作者单位	1.China Agr Univ, Coll Biol Sci, State Key Lab Plant Physiol & Biochem, Beijing 100193, Peoples R China 2.Chinese Acad Sci, Inst Bot, Key Lab Photobiol, Beijing 100093, Peoples R China 3.Wilkes Univ, Dept Biol, Wilkes Barre, PA 18766 USA
推荐引用方式 GB/T 7714	Li, Cong,Qi, Lijuan,Zhang, Shaoman,et al. Mutual upregulation of HY5 and TZP in mediating phytochrome A signaling[J]. PLANT CELL,2022,34(1):633-654.
APA	Li, Cong.,Qi, Lijuan.,Zhang, Shaoman.,Dong, Xiaojing.,Jing, Yanjun.,...&Li, Jigang.(2022).Mutual upregulation of HY5 and TZP in mediating phytochrome A signaling.PLANT CELL,34(1),633-654.
MLA	Li, Cong,et al."Mutual upregulation of HY5 and TZP in mediating phytochrome A signaling".PLANT CELL 34.1(2022):633-654.

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