The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum

doi:10.1242/dev.200892

	The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum
	Yang, Ke-Zhen ; Zuo, Chao-Ran ; Leng, Ya-Jun ; Yue, Jun-Ling ; Liu, Hui -Chao ; Fan, Zhi-Bin ; Xue, Xue-Yi ; Dong, Juan 4,5; Chen, Li-Qun ; Le, Jie1
	2022
发表期刊	DEVELOPMENT
ISSN	0950-1991
卷号	149 期号:17
摘要	Stomata are epidermal pores that control gas exchange between plants and the atmosphere. In Arabidopsis, the ERECTA family (ERECTAf) receptors, including ERECTA, ERECTA-LIKE 1 (ERL1) and ERL2, redundantly play pivotal roles in enforcing the 'one-cell -spacing' rule. Accumulating evidence has demonstrated that the functional specificities of receptors are likely associated with their differential subcellular dynamics. The endoplasmic reticulum (ER)-resident chaperone complex SDF2-ERdj3B-BiP functions in many aspects of plant development. We employed pharmacological treatments combined with cell biological and biochemical approaches to demonstrate that the abundance of ERECTA was reduced in the erdj3b-1 mutant, but the localization and dynamics of ERECTA were not noticeably affected. By contrast, the erdj3b mutation caused the retention of ERL1/ERL2 in the ER. Furthermore, we found that the function of SDF2-ERdj3B-BiP is implicated with the distinct roles of ERECTAf receptors. Our findings establish that the ERECTAf receptor-mediated signaling in stomatal development is ensured by the activities of the ER quality control system, which preferentially maintains the protein abundance of ERECTA and proper subcellular dynamics of ERL1/ERL2, prior to the receptors reaching their destination - the plasma membrane - to execute their functions.
关键词	Arabidopsis Stomatal development ERECTA receptor SDF2-ERdj3B-BiP Molecular chaperone Endoplasmic reticulum quality control
学科领域	Developmental Biology
DOI	10.1242/dev.200892
收录类别	SCI
语种	英语
WOS关键词	PROTEIN-QUALITY CONTROL ; GNOM ARF-GEF ; GLYCAN SIGNAL ; LOCALIZATION ; THALIANA ; REVEALS
WOS研究方向	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000879176600004
出版者	COMPANY BIOLOGISTS LTD
文献子类	Article
出版地	CAMBRIDGE
EISSN	1477-9129
资助机构	National Natural Science Foundation of China ; [31871377] ; [32070723] ; [31970804] ; [32170722] ; [31470279] ; [31872668]
作者邮箱	chenliqun@cau.edu.cn ; lejie@ibcas.ac.cn
作品OA属性	Green Published, Bronze
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/28715
专题	中科院植物分子生理学重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, CAS Ctr Excellence Mol Plant Sci, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.China Agr Univ, Coll Biol Sci, State Key Lab Plant Physiol & Biochem, Beijing 100193, Peoples R China 4.Univ Illinois, Dept Plant Biol, Urbana, IL 61801 USA 5.Rutgers State Univ, Waksman Inst Microbiol, Piscataway, NJ 08854 USA 6.Rutgers State Univ, Dept Plant Biol, New Brunswick, NJ 08901 USA
推荐引用方式 GB/T 7714	Yang, Ke-Zhen,Zuo, Chao-Ran,Leng, Ya-Jun,et al. The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum[J]. DEVELOPMENT,2022,149(17).
APA	Yang, Ke-Zhen.,Zuo, Chao-Ran.,Leng, Ya-Jun.,Yue, Jun-Ling.,Liu, Hui -Chao.,...&Le, Jie.(2022).The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum.DEVELOPMENT,149(17).
MLA	Yang, Ke-Zhen,et al."The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum".DEVELOPMENT 149.17(2022).

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