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| Connected function of PRAF/RLD and GNOM in membrane trafficking controls intrinsic cell polarity in plants | |
Wang, Lu1; Li, Dongmeng1; Yang, Kezhen2; Guo, Xiaoyu; Bian, Chao1,7,8; Nishimura, Takeshi3; Le, Jie2,4 ; Morita, Miyo Terao3; Bergmann, Dominique C.; Dong, Juan1
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| 2022 | |
| 发表期刊 | NATURE COMMUNICATIONS
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| 卷号 | 13期号:1 |
| 摘要 | Cell polarity is a fundamental feature underlying cell morphogenesis and organismal development. In the Arabidopsis stomatal lineage, the polarity protein BASL controls stomatal asymmetric cell division. However, the cellular machinery by which this intrinsic polarity site is established remains unknown. Here, we identify the PRAF/RLD proteins as BASL physical partners and mutating four PRAF members leads to defects in BASL polarization. Members of PRAF proteins are polarized in stomatal lineage cells in a BASL-dependent manner. Developmental defects of the praf mutants phenocopy those of the gnom mutants. GNOM is an activator of the conserved Arf GTPases and plays important roles in membrane trafficking. We further find PRAF physically interacts with GNOM in vitro and in vivo. Thus, we propose that the positive feedback of BASL and PRAF at the plasma membrane and the connected function of PRAF and GNOM in endosomal trafficking establish intrinsic cell polarity in the Arabidopsis stomatal lineage. |
| 学科领域 | Multidisciplinary Sciences |
| DOI | 10.1038/s41467-021-27748-w |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS关键词 | TRANS-GOLGI NETWORK ; PLASMA-MEMBRANE ; SUBCELLULAR-LOCALIZATION ; AUXIN TRANSPORT ; ARF-GEF ; DIVISION ; RAB ; GENE ; PHOSPHORYLATION ; MECHANISMS |
| WOS研究方向 | Science Citation Index Expanded (SCI-EXPANDED) |
| WOS记录号 | WOS:001028235600001 |
| 出版者 | NATURE PORTFOLIO |
| 文献子类 | Article |
| 出版地 | BERLIN |
| EISSN | 2041-1723 |
| 资助机构 | National Institute of Health [GM109080, GM131827] ; National Science Foundation [1851907, 1952823] ; National Natural Science Foundation of China [31771515, 31970804, 31871377] ; Core Research for Evolutional Science and Technology (CREST) award from the Japan Science and Technology Agency (JST) [JPMJCR14M5] |
| 作者邮箱 | dong@waksman.rutgers.edu |
| 作品OA属性 | Green Published, gold |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.ibcas.ac.cn/handle/2S10CLM1/28745 |
| 专题 | 中科院植物分子生理学重点实验室 |
| 作者单位 | 1.Rutgers State Univ, Waksman Inst Microbiol, Piscataway, NJ 08854 USA 2.Rutgers State Univ, Dept Plant Biol, New Brunswick, NJ 08901 USA 3.Chinese Acad Sci, Inst Bot, CAS Ctr Excellence Mol Plant Sci, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China 4.Natl Inst Basic Biol, Div Plant Environm Responses, Okazaki 4448556, Japan 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.Bergmann, Dominique C.] Stanford Univ, Dept Biol, Stanford, CA 94305 USA 7.Bergmann, Dominique C.] Howard Hughes Med Inst, Stanford, CA 94305 USA 8.Univ Calif Davis, Dept Plant Biol, Davis, CA 95616 USA 9.Univ Calif Davis, Genome Ctr, Davis, CA 95616 USA |
| 推荐引用方式 GB/T 7714 | Wang, Lu,Li, Dongmeng,Yang, Kezhen,et al. Connected function of PRAF/RLD and GNOM in membrane trafficking controls intrinsic cell polarity in plants[J]. NATURE COMMUNICATIONS,2022,13(1). |
| APA | Wang, Lu.,Li, Dongmeng.,Yang, Kezhen.,Guo, Xiaoyu.,Bian, Chao.,...&Dong, Juan.(2022).Connected function of PRAF/RLD and GNOM in membrane trafficking controls intrinsic cell polarity in plants.NATURE COMMUNICATIONS,13(1). |
| MLA | Wang, Lu,et al."Connected function of PRAF/RLD and GNOM in membrane trafficking controls intrinsic cell polarity in plants".NATURE COMMUNICATIONS 13.1(2022). |
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| Wang-2022-Connected （12161KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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