The Chromatin-Remodeling Factor PICKLE Integrates Brassinosteroid and Gibberellin Signaling during Skotomorphogenic Growth in Arabidopsis

doi:10.1105/tpc.113.121848

IB-CAS > 中科院光生物学重点实验室

	The Chromatin-Remodeling Factor PICKLE Integrates Brassinosteroid and Gibberellin Signaling during Skotomorphogenic Growth in Arabidopsis
	Zhang, Dong 1; Jing, Yanjun ; Jiang, Zhimin 1; Lin, Rongcheng2
	2014
发表期刊	PLANT CELL
ISSN	1040-4651
卷号	26 期号:6 页码:2472-2485
摘要	Plant cell elongation is controlled by endogenous hormones, including brassinosteroid (BR) and gibberellin (GA), and by environmental factors, such as light/darkness. The molecular mechanisms underlying the convergence of these signals that govern cell growth remain largely unknown. We previously showed that the chromatin-remodeling factor PICKLE/ENHANCED PHOTOMORPHOGENIC1 (PKL/EPP1) represses photomorphogenesis in Arabidopsis thaliana. Here, we demonstrated that PKL physically interacted with PHYTOCHROME-INTERACTING FACTOR3 (PIF3) and BRASSINAZOLE-RESISTANT1 (BZR1), key components of the light and BR signaling pathways, respectively. Also, this interaction promoted the association of PKL with cell elongation-related genes. We found that PKL, PIF3, and BZR1 coregulate skotomorphogenesis by repressing the trimethylation of histone H3 Lys-27 (H3K27me3) on target promoters. Moreover, DELLA proteins interacted with PKL and attenuated its binding ability. Strikingly, brassinolide and GA(3) inhibited H3K27me3 modification of histones associated with cell elongation-related loci in a BZR1- and DELLA-mediated manner, respectively. Our findings reveal that the PKL chromatin-remodeling factor acts as a critical node that integrates light/darkness, BR, and GA signals to epigenetically regulate plant growth and development. This work also provides a molecular framework by which hormone signals regulate histone modification in concert with light/dark environmental cues.
学科领域	Biochemistry & Molecular Biology ; Plant Sciences ; Cell Biology
DOI	10.1105/tpc.113.121848
收录类别	SCI
语种	英语
WOS关键词	HISTONE MODIFICATIONS ; MOLECULAR-MECHANISM ; PLANT-GROWTH ; LIGHT ; PROTEIN ; EXPRESSION ; REPRESSOR ; RESPONSES ; AUXIN ; PIF4
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences ; Cell Biology
WOS记录号	WOS:000341884000013
出版者	AMER SOC PLANT BIOLOGISTS
文献子类	Article
出版地	ROCKVILLE
EISSN	1532-298X
资助机构	National Science Foundation of China [31325002, 31370023] ; Chinese Academy of Sciences
作者邮箱	rclin@ibcas.ac.cn
作品OA属性	Green Published, Bronze
引用统计	被引频次：108[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/27142
专题	中科院光生物学重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Photobiol, Inst Bot, Beijing 100093, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Natl Ctr Plant Gene Res, Beijing 100093, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Dong,Jing, Yanjun,Jiang, Zhimin,et al. The Chromatin-Remodeling Factor PICKLE Integrates Brassinosteroid and Gibberellin Signaling during Skotomorphogenic Growth in Arabidopsis[J]. PLANT CELL,2014,26(6):2472-2485.
APA	Zhang, Dong,Jing, Yanjun,Jiang, Zhimin,&Lin, Rongcheng.(2014).The Chromatin-Remodeling Factor PICKLE Integrates Brassinosteroid and Gibberellin Signaling during Skotomorphogenic Growth in Arabidopsis.PLANT CELL,26(6),2472-2485.
MLA	Zhang, Dong,et al."The Chromatin-Remodeling Factor PICKLE Integrates Brassinosteroid and Gibberellin Signaling during Skotomorphogenic Growth in Arabidopsis".PLANT CELL 26.6(2014):2472-2485.

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