Antioxidant and Antiproliferative Activities of Twenty-Four Vitis vinifera Grapes

doi:10.1371/journal.pone.0105146

	Antioxidant and Antiproliferative Activities of Twenty-Four Vitis vinifera Grapes
	Liang, Zhenchang 1; Cheng, Lailiang 2; Zhong, Gan-Yuan ; Liu, Rui Hai 1
	2014
发表期刊	PLOS ONE
ISSN	1932-6203
卷号	9 期号:8
摘要	Grapes are rich in phytochemicals with many proven health benefits. Phenolic profiles, antioxidant and antiproliferative activities of twenty-four selected Vitis vinifera grape cultivars were investigated in this study. Large ranges of variation were found in these cultivars for the contents of total phenolics (95.3 to 686.5 mg/100 g) and flavonoids (94.7 to 1055 mg/100 g) and antioxidant activities (oxygen radical absorbance capacity 378.7 to 3386.0 mg of Trolox equivalents/100 g and peroxylradical scavenging capacity14.2 to 557 mg of vitamin C equivalents/100 g), cellular antioxidant activities (3.9 to 139.9 mu mol of quercetin equivalents/100 g without PBS wash and 1.4 to 95.8 mu mol of quercetin equivalents/100 g with PBS wash) and antiproliferative activities (25 to 82% at the concentrations of 100 mg/mL extracts). The total antioxidant activities were significantly correlated with the total phenolics and flavonoids. However, no significant correlations were found between antiproliferative activities and total phenolics or total flavonoids content. Wine grapes and color grapes showed much higher levels of phytochemicals and antioxidant activities than table grapes and green/yellow grapes. Several germplasm accessions with much high contents of phenolics and flavonoids, and total antioxidant activity were identified. These germplasm can be valuable sources of genes for breeding grape cultivars with better nutritional qualities of wine and table grapes in the future.
学科领域	Multidisciplinary Sciences
DOI	10.1371/journal.pone.0105146
收录类别	SCI
语种	英语
WOS关键词	ANTI PROLIFERATIVE ACTIVITIES ; WOODCHUCK HEPATITIS-VIRUS ; KAPPA-B ACTIVATION ; CANCER MCF-7 CELLS ; COMMON FRUITS ; RED WINES ; POLYPHENOLS ; ASSAY ; PHYTOCHEMICALS ; PROFILES
WOS研究方向	Science & Technology - Other Topics
WOS记录号	WOS:000341302700077
出版者	PUBLIC LIBRARY SCIENCE
文献子类	Article
出版地	SAN FRANCISCO
资助机构	USDA-ARS ; Cornell University ; United States Department of Agriculture-Agricultural Research Service [1910-21220-004-00D]
作者邮箱	ganyuan.zhong@ars.usda.gov ; rl23@cornell.edu
作品OA属性	Green Published, Green Submitted, gold
引用统计	被引频次：66[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ibcas.ac.cn/handle/2S10CLM1/27313
专题	中科院北方资源植物重点实验室
作者单位	1.Chinese Acad Sci, Inst Bot, Beijing, Peoples R China 2.Cornell Univ, Dept Food Sci, Ithaca, NY 14853 USA 3.Cornell Univ, Dept Hort, Ithaca, NY USA 4.USDA ARS, Grape Genet Res Unit, Geneva, NY 14456 USA
推荐引用方式 GB/T 7714	Liang, Zhenchang,Cheng, Lailiang,Zhong, Gan-Yuan,et al. Antioxidant and Antiproliferative Activities of Twenty-Four Vitis vinifera Grapes[J]. PLOS ONE,2014,9(8).
APA	Liang, Zhenchang,Cheng, Lailiang,Zhong, Gan-Yuan,&Liu, Rui Hai.(2014).Antioxidant and Antiproliferative Activities of Twenty-Four Vitis vinifera Grapes.PLOS ONE,9(8).
MLA	Liang, Zhenchang,et al."Antioxidant and Antiproliferative Activities of Twenty-Four Vitis vinifera Grapes".PLOS ONE 9.8(2014).

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